YRC Public Data Repository - Protein Structure Prediction

Protein:	SPBPB2B2.05
Organism:	Schizosaccharomyces pombe
Length:	237 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPBPB2B2.05.

Description	E-value	Query Range	Subject Range
GUAA_CLOTH - GMP synthase [glutamine-hydrolyzing] OS=Clostridium thermocellum (strain ATCC 27405 / DSM 1237 / NBR...	178.0	[0..5]	[233..21]
gi\|221089178, gi... - gi\|221089178\|ref\|ZP_03558700.1\| GMP synthase, large subunit [Geobacillus sp. Y412MC61], gi\|220706876... GUAA_GEOKA - GMP synthase [glutamine-hydrolyzing] OS=Geobacillus kaustophilus GN=guaA PE=3 SV=1 gi\|229328416, gi... - gi\|229500698\|ref\|ZP_04394346.1\| GMP synthase, large subunit [Geobacillus sp. Y412MC52], gi\|229328416... GUAA_GEOKA - GMP synthase [glutamine-hydrolyzing] OS=Geobacillus kaustophilus (strain HTA426) GN=guaA PE=3 SV=1	173.0	[0..5]	[231..21]
GUAA_BACLD - GMP synthase [glutamine-hydrolyzing] OS=Bacillus licheniformis (strain ATCC 14580 / DSM 13 / JCM 250...	171.0	[0..5]	[233..24]
gi\|228937552, gi... - gi\|228937552\|ref\|ZP_04100193.1\| GMP synthase, large subunit [Bacillus thuringiensis serovar berliner... gi\|228860640, gi... - gi\|228898997\|ref\|ZP_04063272.1\| GMP synthase, large subunit [Bacillus thuringiensis IBL 4222], gi\|22... gi\|228977009, gi... - gi\|228977009\|ref\|ZP_04137416.1\| GMP synthase, large subunit [Bacillus thuringiensis Bt407], gi\|22878... gi\|74490054, gi\|... - gi\|75762461\|ref\|ZP_00742326.1\| GMP synthase (glutamine-hydrolyzing) [Bacillus thuringiensis serovar ... gi\|228789288, gi... - gi\|228970439\|ref\|ZP_04131093.1\| GMP synthase, large subunit [Bacillus thuringiensis serovar thuringi...	169.0	[0..5]	[233..26]
GUAA_BACCR - GMP synthase [glutamine-hydrolyzing] OS=Bacillus cereus (strain ATCC 14579 / DSM 31 / JCM 2152 / NBR... gi\|229125762, gi... - gi\|229125762\|ref\|ZP_04254790.1\| GMP synthase, large subunit [Bacillus cereus BDRD-Cer4], gi\|22865770...	169.0	[0..5]	[233..26]
GUAA_BACC1 - GMP synthase [glutamine-hydrolyzing] OS=Bacillus cereus (strain ATCC 10987 / NRS 248) GN=guaA PE=3 S...	169.0	[0..5]	[233..23]
GUAA_BACHK - GMP synthase [glutamine-hydrolyzing] OS=Bacillus thuringiensis subsp. konkukian (strain 97-27) GN=gu... GUAA_BACHK - GMP synthase [glutamine-hydrolyzing] OS=Bacillus thuringiensis subsp. konkukian GN=guaA PE=3 SV=1	168.0	[0..5]	[233..26]
gi\|254756031 - gi\|254756031\|ref\|ZP_05208062.1\| GMP synthase [Bacillus anthracis str. Vollum] gi\|167530531, gi... - gi\|167634217\|ref\|ZP_02392539.1\| GMP synthase [Bacillus anthracis str. A0442], gi\|167530531\|gb\|EDR932... gi\|254761681 - gi\|254761681\|ref\|ZP_05213699.1\| GMP synthase [Bacillus anthracis str. Australia 94] GUAA_BACC0 - GMP synthase [glutamine-hydrolyzing] OS=Bacillus cereus (strain AH820) GN=guaA PE=3 SV=1 gi\|254735439 - gi\|254735439\|ref\|ZP_05193147.1\| GMP synthase [Bacillus anthracis str. Western North America USA6153] gi\|254744183 - gi\|254744183\|ref\|ZP_05201865.1\| GMP synthase [Bacillus anthracis str. Kruger B] gi\|47777798, gi\|... - gi\|47777798\|ref\|YP_016877.2\| bifunctional GMP synthase/glutamine amidotransferase protein [Bacillus ... gi\|30253765, gi\|... - gi\|30260444\|ref\|NP_842821.1\| bifunctional GMP synthase/glutamine amidotransferase protein [Bacillus ... gi\|21398215 - ref\|NP_654200.1\| GMP_synt_C, GMP synthase C terminal domain [Bacillus anthracis str. A2012] gi\|254686663 - gi\|254686663\|ref\|ZP_05150521.1\| GMP synthase [Bacillus anthracis str. CNEVA-9066] gi\|254724731 - gi\|254724731\|ref\|ZP_05186514.1\| GMP synthase [Bacillus anthracis str. A1055] GUAA_BACAN - GMP synthase [glutamine-hydrolyzing] OS=Bacillus anthracis GN=guaA PE=3 SV=1	168.0	[0..5]	[233..23]
gi\|167640155, gi... - gi\|167640155\|ref\|ZP_02398422.1\| GMP synthase [Bacillus anthracis str. A0193], gi\|167511966\|gb\|EDR873... GUAA_BACAH - GMP synthase [glutamine-hydrolyzing] OS=Bacillus thuringiensis (strain Al Hakam) GN=guaA PE=3 SV=1 gi\|65317699 - gi\|65317699\|ref\|ZP_00390658.1\| COG0519: GMP synthase, PP-ATPase domain/subunit [Bacillus anthracis s... GUAA_BACC3 - GMP synthase [glutamine-hydrolyzing] OS=Bacillus cereus (strain 03BB102) GN=guaA PE=3 SV=1 GUAA_BACCZ - GMP synthase [glutamine-hydrolyzing] OS=Bacillus cereus (strain ZK / E33L) GN=guaA PE=3 SV=1 gi\|228912998, gi... - gi\|228912998\|ref\|ZP_04076640.1\| GMP synthase, large subunit [Bacillus thuringiensis serovar pulsiens... GUAA_BACAC - GMP synthase [glutamine-hydrolyzing] OS=Bacillus anthracis (strain CDC 684 / NRRL 3495) GN=guaA PE=3... gi\|47555911, gi\|... - gi\|47567509\|ref\|ZP_00238221.1\| GMP synthase [Bacillus cereus G9241], gi\|47555911\|gb\|EAL14250.1\| GMP ... gi\|228931760, gi... - gi\|228931760\|ref\|ZP_04094660.1\| GMP synthase, large subunit [Bacillus thuringiensis serovar andalous... gi\|49183286, gi\|... - gi\|49183286\|ref\|YP_026538.1\| bifunctional GMP synthase/glutamine amidotransferase protein [Bacillus ... gi\|228925514, gi... - gi\|228925514\|ref\|ZP_04088606.1\| GMP synthase, large subunit [Bacillus thuringiensis serovar pondiche... gi\|177655761, gi... - gi\|177655761\|ref\|ZP_02937036.1\| GMP synthase [Bacillus anthracis str. A0174], gi\|172079990\|gb\|EDT650... gi\|228693941, gi... - gi\|229089392\|ref\|ZP_04220665.1\| GMP synthase, large subunit [Bacillus cereus Rock3-42], gi\|228693941... gi\|190567444, gi... - gi\|190567444\|ref\|ZP_03020358.1\| GMP synthase [Bacillus anthracis Tsiankovskii-I], gi\|190561571\|gb\|ED... gi\|228815616, gi... - gi\|228944066\|ref\|ZP_04106448.1\| GMP synthase, large subunit [Bacillus thuringiensis serovar monterre... gi\|170687797, gi... - gi\|170687797\|ref\|ZP_02879012.1\| GMP synthase [Bacillus anthracis str. A0465], gi\|170668324\|gb\|EDT190... gi\|229182657, gi... - gi\|229182657\|ref\|ZP_04309901.1\| GMP synthase, large subunit [Bacillus cereus BGSC 6E1], gi\|228600826... gi\|170125863, gi... - gi\|170709230\|ref\|ZP_02899652.1\| GMP synthase [Bacillus anthracis str. A0389], gi\|170125863\|gb\|EDS947... gi\|229154027, gi... - gi\|229154027\|ref\|ZP_04282155.1\| GMP synthase, large subunit [Bacillus cereus ATCC 4342], gi\|22862944... gi\|196022949, gi... - gi\|196046204\|ref\|ZP_03113431.1\| GMP synthase [Bacillus cereus 03BB108], gi\|196022949\|gb\|EDX61629.1\| ... GUAA_BACAA - GMP synthase [glutamine-hydrolyzing] OS=Bacillus anthracis (strain A0248) GN=guaA PE=3 SV=1 gi\|195990540, gi... - gi\|196036858\|ref\|ZP_03104246.1\| GMP synthase [Bacillus cereus W], gi\|195990540\|gb\|EDX54520.1\| GMP sy... gi\|196028073, gi... - gi\|196041138\|ref\|ZP_03108434.1\| GMP synthase [Bacillus cereus NVH0597-99], gi\|196028073\|gb\|EDX66684....	168.0	[0..5]	[233..26]
GUAA_MOOTA - GMP synthase [glutamine-hydrolyzing] OS=Moorella thermoacetica (strain ATCC 39073) GN=guaA PE=3 SV=1	167.0	[0..5]	[231..27]

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Predicted Domain #1

Region A:
Residues: [1-237]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPYVEAIIKA GGCPIVIYPG LQRNSIPPNI DGIILAGGES VHPNRYGEDF DPNAPKSVDV  60
   61 IRDSTEWGMI DFALKKKIPI LGICRGCQVL NVYFGGSLYQ NVSSCGFRDI HRPSKPRHYL 120
  121 AHKVMAKPGK LKNILGSNVI DVNSIHDQGI KTLGMGLQST VISDDGLCEG IESKDGLIIG 180
  181 VQWHPEAIID KQPHSLKLFQ YFINRSKWHM KQSNIFSNVP HESSFYRNSI ISIPIAP

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	38.69897
Match:	1gpmA
Description:	GMP synthetase; GMP synthetase, central domain; GMP synthetase C-terminal dimerisation domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
ligase activity	1.86890906127173	bayes_pls_golite062009
catalytic activity	1.30391542469987	bayes_pls_golite062009
anthranilate synthase activity	1.21184543688778	bayes_pls_golite062009
oxo-acid-lyase activity	0.0620506742330145	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: