YRC Public Data Repository - Protein Structure Prediction

Protein:	SPAC4D7.06c
Organism:	Schizosaccharomyces pombe
Length:	264 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPAC4D7.06c.

Description	E-value	Query Range	Subject Range
CYSG_PHOLL - Siroheme synthase OS=Photorhabdus luminescens subsp. laumondii GN=cysG PE=3 SV=1 CYSG_PHOLL - Siroheme synthase OS=Photorhabdus luminescens subsp. laumondii (strain DSM 15139 / CIP 105565 / TT01...	255.0	[0..14]	[264..4]
CYSG_PSEA7 - Siroheme synthase OS=Pseudomonas aeruginosa (strain PA7) GN=cysG PE=3 SV=1	249.0	[0..14]	[264..4]
CYSG_ECO24 - Siroheme synthase OS=Escherichia coli O139:H28 (strain E24377A / ETEC) GN=cysG PE=3 SV=1 CYSG_ECOSE - Siroheme synthase OS=Escherichia coli (strain SE11) GN=cysG PE=3 SV=1 CYSG_ECO8A - Siroheme synthase OS=Escherichia coli O8 (strain IAI1) GN=cysG PE=3 SV=1	247.0	[0..14]	[264..4]
CYSG_SHIB3 - Siroheme synthase OS=Shigella boydii serotype 18 (strain CDC 3083-94 / BS512) GN=cysG PE=3 SV=1 CYSG_SHIBS - Siroheme synthase OS=Shigella boydii serotype 4 (strain Sb227) GN=cysG PE=3 SV=1	247.0	[0..14]	[264..4]
gi\|24053835, gi\|... - gi\|24114633\|ref\|NP_709143.1\| siroheme synthase [Shigella flexneri 2a str. 301], gi\|24053835\|gb\|AAN44... CYSG_SHIF8 - Siroheme synthase OS=Shigella flexneri serotype 5b (strain 8401) GN=cysG PE=3 SV=1 gi\|30065346, gi\|... - gi\|30065346\|ref\|NP_839517.1\| siroheme synthase [Shigella flexneri 2a str. 2457T], gi\|30043608\|gb\|AAP... CYSG_SHISS - Siroheme synthase OS=Shigella sonnei (strain Ss046) GN=cysG PE=3 SV=1 CYSG_SHIFL - Siroheme synthase OS=Shigella flexneri GN=cysG PE=3 SV=1	247.0	[0..14]	[264..4]
CYSG_ECOL5 - Siroheme synthase OS=Escherichia coli O6:K15:H31 (strain 536 / UPEC) GN=cysG PE=3 SV=1 gi\|191171534, gi... - gi\|75241536\|ref\|ZP_00725381.1\| COG0007: Uroporphyrinogen-III methylase [Escherichia coli F11], gi\|19...	247.0	[0..14]	[264..4]
CYSG2_YERPS - Siroheme synthase 2 OS=Yersinia pseudotuberculosis GN=cysG2 PE=3 SV=1 CYSG2_YERPS - Siroheme synthase 2 OS=Yersinia pseudotuberculosis serotype I (strain IP32953) GN=cysG2 PE=3 SV=1 gi\|170022493, gi... - gi\|170022493\|ref\|YP_001718998.1\| siroheme synthase [Yersinia pseudotuberculosis YPIII], gi\|169749027... CYSG2_YERP3 - Siroheme synthase 2 OS=Yersinia pseudotuberculosis serotype O:1b (strain IP 31758) GN=cysG2 PE=3 SV=...	247.0	[0..14]	[264..4]
CYSG_ECO45 - Siroheme synthase OS=Escherichia coli O45:K1 (strain S88 / ExPEC) GN=cysG PE=3 SV=1 CYSG_ECOK1 - Siroheme synthase OS=Escherichia coli O1:K1 / APEC GN=cysG PE=3 SV=1 CYSG_ECOUT - Siroheme synthase OS=Escherichia coli (strain UTI89 / UPEC) GN=cysG PE=3 SV=1 gi\|226902365, gi... - gi\|237703101\|ref\|ZP_04533582.1\| siroheme synthase [Escherichia sp. 3_2_53FAA], gi\|226902365\|gb\|EEH88...	247.0	[0..14]	[264..4]
gi\|126194422, gi... - gi\|84326938\|ref\|ZP_00974962.1\| COG0007: Uroporphyrinogen-III methylase [Pseudomonas aeruginosa 2192]...	246.0	[0..14]	[264..4]
gi\|581142 - gi\|581142\|emb\|CAA32419.1\| unnamed protein product [Escherichia coli]	246.0	[0..14]	[264..4]

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Predicted Domain #1

Region A:
Residues: [1-264]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MASKYQSVQP GGSLIIAWRA QGKKVLIVGG GVVAAGRILH VLNADAHVIV VSPKAGLCKE  60
   61 VAWRIQEKQV EWRDRGFLVE DLSDDVNMVL TAIDDPSLSS EIYKLCKSKK IPVNAADIPP 120
  121 ECDFYFGSEI RNGPLQIMVS TNGKGPKLAS LIRKKIESSI NPATGMALEK TGLLRQKLRD 180
  181 IVPEPENSRK RMRWMIEICE LWSLEELAML DENLINRLLG YFPKKTPSYR EITTPAYSKI 240
  241 DNYIWFGAII ISGAVLLKHV SKAR

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	64.69897
Match:	1pjqA
Description:	Structure and function of CysG, the multifunctional methyltransferase/dehydrogenase/ferrochelatase for siroheme synthesis
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	1.79741889688267	bayes_pls_golite062009
oxidoreductase activity	0.120113583068184	bayes_pls_golite062009
nucleic acid binding	0.100470710829263	bayes_pls_golite062009
DNA binding	0.0870043837215047	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: