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View Structure Prediction Details

Protein: jmj2
Organism: Schizosaccharomyces pombe
Length: 715 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for jmj2.

Description E-value Query
Range
Subject
Range
KDM5C_CANLF - Lysine-specific demethylase 5C OS=Canis lupus familiaris GN=KDM5C PE=2 SV=1
661.0 [0..47] [713..1]
JD1C_MOUSE, JAD1... - (P41230) Jumonji/ARID domain-containing protein 1C (SmcX protein) (Xe169 protein), Jumonji/ARID doma...
660.0 [0..51] [713..5]
gi|109130908 - gi|109130908|ref|XP_001090508.1| PREDICTED: similar to Smcx homolog, X chromosome [Macaca mulatta]
660.0 [0..47] [713..1]
gi|109511645 - gi|109511645|ref|XP_001064297.1| PREDICTED: similar to jumonji, AT rich interactive domain 1C (Rbp2 ...
659.0 [0..51] [713..5]
KDM5C - lysine (K)-specific demethylase 5C
659.0 [0..47] [713..1]

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Predicted Domain #1
Region A:
Residues: [1-106]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSKSTFHQTS PSFVQYTHAT DKLKPAPHGM NTRGNNLSSM SKNTGQRKQR SKSIHGLPVA  60
   61 PVFYPDKEEF QDSIGYINKI APIGEKYGII KIVPPAGWNP PMQLDM

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 3.61
Match: 2oq6A
Description: No description for 2oq6A was found.

Predicted Domain #2
Region A:
Residues: [107-257]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NKFSFRTRRQ DLHMMDLRFR EIVSYDERVY RFFCNLGMEL PESFFISNTS IDLYSLMRCI  60
   61 DSHASLSEKE LKVHVWKRIL RELSIPFTNA SLKEASDLYL RYIFPFEDFV RKYQTSEDQC 120
  121 FETDLFPKFF TKDEHSNISI KDQKTSKQFN P

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 23.522879
Match: 1kqqA
Description: DNA-binding domain from the dead ringer protein
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [258-335]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ETNESVGILQ NQESKRNEQI KQQYMPADNF GSNDNHSHNK KRRLSSLSTN NNHLCDNCHK  60
   61 PVNCEVEDTC KEAYCTKC

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [336-612]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IINPYEFGFE TGNYYTLSNF EKYCDNFKKN YFSKFKDSEI TEDIVEKEYW KLVKDNNTSL  60
   61 EVEYGADLST LDQGSAFPSL AKNPVNPYSK DTWNLNVIAS TNGSLLSYID NPVSGITCPW 120
  121 LYVGMCFSTF CWHVEDNYTY SVNYQHYGDT KLWYGIPGDQ AERFERAALD IAPDLVKKQK 180
  181 DLLYQLATMI NPDELQKRGV DVYFIDQGPN EFVITFPKSF HAGINHGFNI NEAVNFAPKD 240
  241 WLLNGFSLNG VLKYQSLLKP PVLSHDMLVY NLATNPA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 66.69897
Match: 2oq6A
Description: No description for 2oq6A was found.

Predicted Domain #5
Region A:
Residues: [613-715]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SEISVSELRP WVHEAVKREL GIRIMIRGRY DLKEILYREL MEDAENWQCQ HCKAFSYFSQ  60
   61 VACSCKSITV CPLHIEYLCK CDLSNKTLRL KVDDNELQKL LSY

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.662 0.967 nuclear chromatin a.4.1 Homeodomain-like


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle