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View Structure Prediction Details

Protein: SPAC4A8.10
Organism: Schizosaccharomyces pombe
Length: 723 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPAC4A8.10.

Description E-value Query
Range
Subject
Range
gi|68468120, gi|... - gi|68468120|ref|XP_721899.1| hypothetical protein CaO19.3991 [Candida albicans SC5314], gi|68467803|...
orf19.11474, orf... - orf19.3991 CGDID:CAL0003171 Assembly 19, Contig19-10194 (183088, 180839) CDS, reverse complemented, ...
517.0 [0..81] [722..36]
gi|44982326, gi|... - gi|45187588|ref|NP_983811.1| ADL285Cp [Ashbya gossypii ATCC 10895], gi|44982326|gb|AAS51635.1| ADL28...
gi|44982326 - gi|44982326|gb|AAS51635.1| ADL285Cp [Ashbya gossypii ATCC 10895]
487.0 [0..80] [719..15]
ROG1 - Protein with putative serine active lipase domain
ROG1_YEAST - Putative lipase ROG1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ROG1 PE=1 SV=1
472.0 [0..80] [689..15]
gi|67904846, gi|... - gi|67904846|ref|XP_682679.1| hypothetical protein AN9410.2 [Aspergillus nidulans FGSC A4], ref|XP_41...
459.0 [0..81] [719..56]
gi|46121381, gi|... - gi|46121381|ref|XP_385245.1| hypothetical protein FG05069.1 [Gibberella zeae PH-1], gi|42551565|gb|E...
439.0 [0..81] [714..869]
gi|49658122, gi|... - gi|50427679|ref|XP_462452.1| hypothetical protein DEHA0G22231g [Debaryomyces hansenii CBS767], gi|49...
432.0 [0..67] [722..4]

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Predicted Domain #1
Region A:
Residues: [1-232]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTISSGENIS KQISENNSST NPKHANSESS PLLSSDFSSS SKDYHKVGAF TDNTNAINIP  60
   61 EQTRGVSHTS SSPSVGTSFS SINLREVKNP LAGSDSTAPF INSTNSVLWI RVRNREARFR 120
  121 QAAYLQGPFT LCVSVWNDQF FDEKNSLLNF DPQVQPSTSF WVCVPYSCFS NQQPIYIEIA 180
  181 SQAIFKDRSI NFELAISQSQ HSIRAMSAAD IDTLHAFPAL HVEHQTPENL WR

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [233-478]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LPYSSFHSKN SHLVVLTHGM HSNVGADMEY LKEKLIESSK SVKELVVVRG FTGNYCQTEK  60
   61 GVRWLGKRLG EWLLDITGWG SASFPRYSHI SVVAHSLGGL VQTYAVGYVH AKTHGAFFQA 120
  121 IHPVFFVTLA TPWLGVAGEH PSYIGKALSY GIIGKTGQDL SLTPLNHSIE SRPFLVLMSD 180
  181 PSTPFFQAVS FFEKRILFAN TTNDYIVPFG TSAMEVSSLG KVEEAEGSDK VMPTHMENGI 240
  241 SPTLKE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 26.69897
Match: 1pjaA
Description: The crystal structure of palmitoyl protein thioesterase-2 reveals the basis for divergent substrate specificities of the two lysosomal thioesterases (PPT1 and PPT2)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
hydrolase activity 1.75934962198703 bayes_pls_golite062009
catalytic activity 1.39629727416851 bayes_pls_golite062009
hydrolase activity, acting on ester bonds 1.26285573204791 bayes_pls_golite062009
lipase activity 0.849473630399459 bayes_pls_golite062009
carboxylesterase activity 0.424330502936163 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [479-723]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NEQTVQSVGD NAKKIHASSE ESGSSFSKAL KSFVGLFSYS ASKTTDTEIP LVKNEDENAR  60
   61 KPTEPNCLGS DELDVSNSSN QFFCSAPKLD PTSTFSGVAQ RVVNTFTNLF IPAVPTDSYF 120
  121 FKYHLHKVVV SDNVHDPAAS FSTFDGITEL NNMNNGFLSN EITIAKNWHR LAWRKVAVRL 180
  181 DGDAHNTMIV RRRFPNAYGW TVIKHLTEIL FEQNTSTAYM NPISFDETTT AAWLSEIYED 240
  241 NSISV

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle