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View Structure Prediction Details

Protein: SPBC17D1.07c
Organism: Schizosaccharomyces pombe
Length: 962 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPBC17D1.07c.

Description E-value Query
Range
Subject
Range
gi|40674640, gi|... - gi|84570003|gb|AAI10812.1| IQGAP1 protein [Homo sapiens], gi|62089472|gb|AAH20549.1| IQGAP1 protein ...
294.0 [0..26] [358..6]
gi|114659004 - gi|114659004|ref|XP_523157.2| PREDICTED: IQ motif containing GTPase activating protein 1 [Pan troglo...
294.0 [0..26] [358..50]
IQG1_MOUSE, IQGA... - Ras GTPase-activating-like protein IQGAP1 OS=Mus musculus GN=Iqgap1 PE=1 SV=1, (Q9JKF1) Ras GTPase-a...
294.0 [0..25] [361..5]

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Predicted Domain #1
Region A:
Residues: [1-218]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKMLQNKGPL QELTLNAMAP NGIFQDEPMI QKFENHYVFK KDMKSKRNKE VKNQMNDWLA  60
   61 YGYLCSVHEA KKWLEEETNN EYQNLDDFVD ALVNGKVLCQ LAFKYYPKLA SNWKPRYQIS 120
  121 ERNTVYLNAF FHFLDFIGMF TPFRFETKDL VRRFNIPKVI YCLHALSYLL DFLEVTRHVP 180
  181 SLYGKLRIKK SQLNTATKEI SLLKKAKKFP NFPKLKNF

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 42.69897
Match: 1p5sA
Description: STRUCTURE AND FUNCTION OF THE CALPONIN-HOMOLOGY DOMAIN OF AN IQGAP PROTEIN FROM SCHIZOSACCHAROMYCES POMBE
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [219-356]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FCSYSHRHET ATSNKQVSCF REVPAWIKQC QSQCRGFLTR KCVSIEKLRR DDMSERLGWL  60
   61 PKLETKLSSI SDEERLILLK ESHQIYRKMV SLHLELLHLP QLEMSLDFCG FSSDDSSIAI 120
  121 SSQLVPPILN NLIFKLEE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 38.30103
Match: 1f5xA
Description: RhoGEF Vav
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [357-554]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SPQIWILIIS RFSSDGIDKI DVQNFILLIL KFFGFAISAS DRRSFLNLIM SCVMVSIQQS  60
   61 SAEVGHSTSD SLISWASRLF TKGFWYAISF GVFSNCFSLQ LQSFFEKHLG NVVDKFFLEH 120
  121 LCETTIESDA MRVVTEMLVS CYENRERIPN ELPMVLKQIY YSRSESFKPS AIKEFIEYFL 180
  181 CDQLMNCLSV YYSKYFEG

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [555-637]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KDSKKFTLVK HFMNSLFGRV KLNEQTEIIW HTRNYRIVEA LVRKLIHLST PKIIPVYGGR  60
   61 TLSCTHKDIF DLQNILRYCD ERG

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [638-827]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DFSSFPSFKK LISLLGSPKL FKKHENQILL LESKNEVIHS SLPCSKSSLY QLSLSLCIPL  60
   61 IEGHLRNSLE EILFGVPTEL ENQKFMSVLR NDKLIKSIHP GSLSGISNSF VNSKHPIEQW 120
  121 QSRLRKILHL FSGRNEDIAS LQCVLQFGSS ERIHLEDIQN SHRYLCSLKK NNSQKDIHRN 180
  181 PLLSHVFDTN 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #6
Region A:
Residues: [828-962]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TKSFDTLKTL NYKHAILKKS MGELYKMEMI HECPRQLFGQ ILVVYLNRER TLLNFYLIEN  60
   61 SKTIDEATLQ LTDLIQAIKT GIYYLRMFNL PFHVKQLYTW LAPISKYDSE ISFNQKKERR 120
  121 KTFLSFERRG KNRKF

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


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Created and Maintained by: Michael Riffle