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View Structure Prediction Details

Protein: pol4
Organism: Schizosaccharomyces pombe
Length: 506 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for pol4.

Description E-value Query
Range
Subject
Range
gi|114632437, gi... - gi|114632437|ref|XP_001170003.1| PREDICTED: polymerase (DNA directed), lambda isoform 10 [Pan troglo...
532.0 [0..4] [504..52]
gi|10732732 - gi|10732732|gb|AAG22519.1|AF283478_1 DNA polymerase beta2 [Homo sapiens]
530.0 [0..4] [504..41]
gi|109090326, gi... - gi|109090328|ref|XP_001110826.1| PREDICTED: polymerase (DNA directed), lambda isoform 13 [Macaca mul...
529.0 [0..4] [504..41]
DPOLL_MACFA - DNA polymerase lambda OS=Macaca fascicularis GN=POLL PE=2 SV=1
528.0 [0..4] [504..41]
DPOLL_MOUSE - DNA polymerase lambda OS=Mus musculus GN=Poll PE=2 SV=1
521.0 [0..4] [504..40]
DPOLL_RAT - DNA polymerase lambda OS=Rattus norvegicus GN=Poll PE=2 SV=1
515.0 [0..4] [504..40]
gi|76654812 - gi|76654812|ref|XP_600587.2| PREDICTED: similar to DNA polymerase lambda (Pol Lambda) (DNA polymeras...
504.0 [0..4] [504..60]

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Predicted Domain #1
Region A:
Residues: [1-175]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKILASSTNY VLHNRLSNSQ YEDARSKIVN FGGEFTNDAA KADYIFVNYS QINRVRRELR  60
   61 TIGTPLETCV SCKLIVKIDW LNEPKESLTP GNPYVIWHRK PEMKVGSPYT PSTRPASHTE 120
  121 APNDFENHET PNTENNNEVK SIDNVDQEGS VYPTTKEYPY VLEIPRYACQ RKTPL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 16.30103
Match: 2dunA
Description: No description for 2dunA was found.

Predicted Domain #2
Region A:
Residues: [176-506]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KCVNQAFVNA LSVLKTCREV NGESVRTRAY GMAIATIKAF PLPIDSAEQL EKMPGCGPKI  60
   61 VHLWKEFAST GTLKEAEEFQ KDPASKILLL FYNIFGVGAS HAAEWYQKGW RTIEQVRKHK 120
  121 DSFTKQIKVG LEFYEDFCKT VTIEEATEIY ETIVSRMPDG IKIQSCLVGG FRRGKPVGAD 180
  181 VDMVLSPSHT HSTKHLVDVL LRILDEEFQF RLISVQEHSC GGKKGYVMLA VILSNSSKIN 240
  241 RRVDIIVVPP AYIGSAVLGW SGGIFFLRDL KLYANSHLGL SYDSFEIINL KTGKDICPDE 300
  301 FNEWKDPVEA EKDIFRYFSL EYIEPKFRNT G

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 113.0
Match: 1jmsA
Description: Terminal deoxynucleotidyl transferase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
DNA-directed DNA polymerase activity 5.14301767080098 bayes_pls_golite062009
DNA polymerase activity 5.09523809908438 bayes_pls_golite062009
nucleotidyltransferase activity 2.75404349131504 bayes_pls_golite062009
catalytic activity 0.60409960326459 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle