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View Structure Prediction Details

Protein: ure2
Organism: Schizosaccharomyces pombe
Length: 835 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ure2.

Description E-value Query
Range
Subject
Range
gi|14599161, gi|... - gi|32170831|gb|AAO85883.1| leaf ubiquitous urease [Glycine max], gi|14599161|emb|CAC43845.1| urease ...
1044.0 [0..1] [835..3]
gi|14599435 - gi|14599435|emb|CAC43859.1| urease [Solanum tuberosum]
1030.0 [0..1] [835..3]
UREA_CANEN - Urease OS=Canavalia ensiformis PE=1 SV=3
1027.0 [0..1] [835..3]
UREA_ASPFU - Urease OS=Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) GN=ure1 PE=2...
UREA_ASPFU - Urease OS=Aspergillus fumigatus GN=ure1 PE=2 SV=2
1016.0 [0..1] [835..3]

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Predicted Domain #1
Region A:
Residues: [1-258]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQPRELHKLT LHQLGSLAQK RLCRGVKLNK LEATSLIASQ IQEYVRDGNH SVADLMSLGK  60
   61 DMLGKRHVQP NVVHLLHEIM IEATFPDGTY LITIHDPICT TDGNLEHALY GSFLPTPSQE 120
  121 LFPLEEEKLY APENSPGFVE VLEGEIELLP NLPRTPIEVR NMGDRPIQVG SHYHFIETNE 180
  181 KLCFDRSKAY GKRLDIPSGT AIRFEPGVMK IVNLIPIGGA KLIQGGNSLS KGVFDDSRTR 240
  241 EIVDNLMKQG FMHQPESP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 104.0
Match: 1e9yA
Description: Urease, beta-subunit; Urease, gamma-subunit
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
nickel ion binding 1.80580363718742 bayes_pls_golite062009
catalytic activity 0.907182340515553 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [259-835]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LNMPLQSARP FVVPRKLYAV MYGPTTNDKI RLGDTNLIVR VEKDFTEYGN ESVFGGGKVI  60
   61 RDGTGQSSSK SMDECLDTVI TNAVIIDHTG IYKADIGIKN GYIVGIGKAG NPDTMDNIGE 120
  121 NMVIGSSTDV ISAENKIVTY GGMDSHVHFI CPQQIEEALA SGITTMYGGG TGPSTGTNAT 180
  181 TCTPNKDLIR SMLRSTDSYP MNIGLTGKGN DSGSSSLKEQ IEAGCSGLKL HEDWGSTPAA 240
  241 IDSCLSVCDE YDVQCLIHTD TLNESSFVEG TFKAFKNRTI HTYHVEGAGG GHAPDIISLV 300
  301 QNPNILPSST NPTRPFTTNT LDEELDMLMV CHHLSRNVPE DVAFAESRIR AETIAAEDIL 360
  361 QDLGAISMIS SDSQAMGRCG EVISRTWKTA HKNKLQRGAL PEDEGSGVDN FRVKRYVSKY 420
  421 TINPAITHGI SHIVGSVEIG KFADLVLWDF ADFGARPSMV LKGGMIALAS MGDPNGSIPT 480
  481 VSPLMSWQMF GAHDPERSIA FVSKASITSG VIESYGLHKR VEAVKSTRNI GKKDMVYNSY 540
  541 MPKMTVDPEA YTVTADGKVM ECEPVDKLPL SQSYFIF

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 177.0
Match: 1ef2A
Description: alpha-Subunit of urease; alpha-subunit of urease, catalytic domain
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle