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View Structure Prediction Details

Protein: prp1
Organism: Schizosaccharomyces pombe
Length: 906 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for prp1.

Description E-value Query
Range
Subject
Range
CG6841-PA - This gene is referred to in FlyBase by the symbol Dmel\CG6841 (CG6841, FBgn0036828). It is a protein...
gi|220950366 - gi|220950366|gb|ACL87726.1| CG6841-PA [synthetic construct]
429.0 [0..2] [906..11]
gi|54641661, gi|... - gi|54641661|gb|EAL30411.1| GA19898-PA [Drosophila pseudoobscura], gi|125977754|ref|XP_001352910.1| G...
427.0 [0..2] [906..11]
gi|47086729, gi|... - gi|47086729|ref|NP_997820.1| PRP6 pre-mRNA processing factor 6 [Danio rerio], gi|34784057|gb|AAH5671...
423.0 [0..1] [901..11]
gi|71895939, gi|... - gi|71895939|ref|NP_001025642.1| MGC97740 protein [Xenopus (Silurana) tropicalis], gi|60550964|gb|AAH...
422.0 [0..1] [901..33]
gi|91088509 - gi|91088509|ref|XP_971592.1| PREDICTED: similar to pre-mRNA-splicing factor prp1 [Tribolium castaneu...
421.0 [0..1] [904..9]
gi|73992767 - gi|73992767|ref|XP_534481.2| PREDICTED: similar to U5 snRNP-associated 102 kDa protein [Canis famili...
420.0 [0..1] [901..60]
gi|157126009, gi... - gi|157126009|ref|XP_001654491.1| pre-mrna splicing factor [Aedes aegypti], gi|108873417|gb|EAT37642....
420.0 [0..2] [906..11]
PRP6_RAT - Pre-mRNA-processing factor 6 OS=Rattus norvegicus GN=Prpf6 PE=1 SV=1
420.0 [0..1] [901..1]
PRP6_MOUSE - Pre-mRNA-processing factor 6 OS=Mus musculus GN=Prpf6 PE=1 SV=1
419.0 [0..1] [901..1]

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Predicted Domain #1
Region A:
Residues: [1-164]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MANFYPDFLN MQPPPNYVAG LGRGATGFTT RSDLGPAQEL PSQESIKAAI EQRKSEIEEE  60
   61 EDIDPRYQDP DNEVALFATA PYDHEDEEAD KIYQSVEEHL SKRRKSQREK QEQLQKEKYE 120
  121 KENPKVSSQF ADLKRGLSTL TDEDWNNIPE PGDLTRKKRT KQPR

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 91.920819
Match: PF06424.3
Description: No description for PF06424.3 was found.

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [165-227]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RERFYATSDF VLASARNENQ AISNFAVDTQ AGTETPDMNG TKTNFVEIGA ARDKVLGIKL  60
   61 AQA

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [228-726]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SSNLTSPSTI DPKGYLTSLN SMVPKNANDL GDIRKARKLL QSVIETNPKH ASGWVAAARL  60
   61 EEVANKLSQA QSLILKGCEN CSRSEDVWLE AIRLHPAAEA KVIIANAVKK LPKSVTLWLE 120
  121 AEKLENQAQH KKRIIKKALE FNPTSVSLWK EAVNLEEEVD NARILLARAV ELIPMSIDLW 180
  181 LALARLETYE NAKKVLNKAR QTIRTSHEVW IAAARLEEQQ GNVSRVEKIM ARGVSELQAT 240
  241 GGMLQRDQWL SEAEKCETEG AVITAQAIIN TCLGVGLDEE DQFDTWLDDA QSFIARKCID 300
  301 CARAVFAFSL RVYPKSEKLW LRAVELEKLY GTTESVCSIL EKAVESCPKA EILWLLYAKE 360
  361 RKNVNDIAGA RNILGRAFEY NSNSEEIWLA AVRIEFVNNE NERARKLLAR ARIESGTERI 420
  421 WTKSISLERI LDEKDRALQL LENALKIYPH YDKLYMMKGQ IFEDKEQIEL ARDAYLAGTK 480
  481 VCPYSIPLWL LLAKLEEKQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 26.69897
Match: 2gw1A
Description: No description for 2gw1A was found.

Predicted Domain #4
Region A:
Residues: [727-906]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SVIRARVVFD RAKVKNPKNE FLWLELIKME LRAGNISQVR AALAKALQEC PSSGLLWTEA  60
   61 IWLEPRAQRK TRATDALRKC EGNAHLLCTI ARMLWLEKKA DKARSWFLKA VKADQDNGDV 120
  121 WCWFYKYSLE AGNEDQQKEV LTSFETADPH HGYFWPSITK DIKNSRKTPQ ELLHLAINVL 180
  181 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 51.69897
Match: 1w3bA
Description: The superhelical TPR domain of O-linked GlcNAc transferase reveals structural similarities to importin alpha.
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle