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View Structure Prediction Details

Protein: pds5
Organism: Schizosaccharomyces pombe
Length: 1205 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for pds5.

Description E-value Query
Range
Subject
Range
gi|73993417 - gi|73993417|ref|XP_543139.2| PREDICTED: similar to androgen-induced prostate proliferative shutoff a...
863.0 [0..17] [1202..200]
gi|109120446 - gi|109120446|ref|XP_001118201.1| PREDICTED: similar to androgen-induced prostate proliferative shuto...
859.0 [0..17] [1202..105]
gi|114649463 - gi|114649463|ref|XP_509623.2| PREDICTED: androgen-induced prostate proliferative shutoff associated ...
852.0 [0..17] [1202..65]
gi|20521718 - gi|20521718|dbj|BAA76823.2| KIAA0979 protein [Homo sapiens]
850.0 [0..17] [1202..61]
PDS5B_MOUSE - Sister chromatid cohesion protein PDS5 homolog B OS=Mus musculus GN=Pds5b PE=1 SV=1
847.0 [0..17] [1202..25]

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Predicted Domain #1
Region A:
Residues: [1-60]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIKLQFQRNI VPTHDNPLTT SEILKRLRDL LGELTSLSQD TIDRDSVLPV ARSLVNNNLL  60
   61 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 67.154902
Match: 1b3uA
Description: Constant regulatory domain of protein phosphatase 2a, pr65alpha
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [61-532]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HHKDKGIRSY TLCCIVELLR LCAPDAPFTL SQLEDIFQVI LKILSGLMNQ ESTYYPQIYE  60
   61 ILESLSNVKS AVLIVDLPNA EEFLVNIFRL FFDLARKGTT KNVEFYMLDI INQLINEINT 120
  121 IPAAALNILF AQLISGKGVR QTIGSSDSTN HGPAFQLARN IFHDSADRLQ RYVCQYFSDI 180
  181 IFDSRDSLSD SMTTPEFIFS HNLVLQLWKY APTTLLNIIP QFENELQAEQ TSVRLVAIET 240
  241 VGLMLQDNAI WSDYPRVWSA FCGRLNDKSV ACRIKCIEVA SNALQNSLAT SEIIENVVQM 300
  301 LQSKLADTDE KVRVATLKTI EQLTFETFKM QFSVQALKLM GDRLRDRKLN VRLQAIRTLS 360
  361 QIYNRAYQDL IDGVEYSIQM FSWIPSSLLE VFYVNDETTN AAVEICMAEL VLQYLSSDTQ 420
  421 TRLNRLFLSI KYFSEKAMRV FILLLQRQVK YSELLNYYIE CCKNYNGGVM DN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 28.69897
Match: 1u6gC
Description: Crystal Structure of The Cand1-Cul1-Roc1 Complex
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [533-688]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DEESITNKLK KVIDIISSKS SNPTLTEATF RKFAELNDRQ SYKMLLQTFS IKSEYQVVLK  60
   61 SIKYLFKRVS ETLSTASLEC FRIFVYRSAL FAFNKSNVHE IIQLLNEPVK YHNFLKPSEA 120
  121 LLQHLPLIHP NIYGEVVIEV ENIIVSSGIE SDPKVI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 19.0
Match: 2c1tA
Description: Structure of the Kap60p:Nup2 complex
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [689-811]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KALSQFSKRK KNFSIQTTTA EILRKLCLHG TQEQAKQAAT IIAITETKEF KLDMITNIVE  60
   61 NLEYNGGLPV RLMTLGQLFL YTLEEVEKVA DQVTEFLVKK VIQRFPEKYD DTHNDEEWCT 120
  121 YEK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 76.69897
Match: 1w63B
Description: AP1 clathrin adaptor core
Matching Structure (courtesy of the PDB):

Predicted Domain #5
Region A:
Residues: [812-908]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LDNLTMCKVL AIRVLVNRLR AAAGGTEALN IGAPIIKLLK VLLMADGELS PFKNTPKISR  60
   61 AYLRLTASKY FLKLCSIPFY AEHIDFSSYV QISLLCQ

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #6
Region A:
Residues: [909-1090]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DENFDVRNLF LTKLQKQLQL KKLPISYYPL LFLTAVDPEE EIKTKASIWI RSQVAFFQKT  60
   61 HDFTMEYVAT YLIHLLSHHP DISSIESENS LDFIAYIRFY VDTVVNSENV PIVFHLMQRI 120
  121 KQSYDVIEDG NNYIYVLSDM AQKILQVKSQ NFGWSLTTYP KQIKLPYEIL RPIPSIDEKK 180
  181 RI

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #7
Region A:
Residues: [1091-1205]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FNKIFITPKM ESQIEHAIRT PVSSFAKQTT NKHANLKQKK THSSKSDKKS SRRRKNEKRR  60
   61 KLNEQNPNIR NVPERSSSRF QGIRINYSEA PSSSEEISEE EEEISEEDFD EIEDL

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


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Created and Maintained by: Michael Riffle