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View Structure Prediction Details

Protein: med7
Organism: Schizosaccharomyces pombe
Length: 376 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for med7.

Description E-value Query
Range
Subject
Range
gi|6474201 - gi|6474201|dbj|BAA87232.1| Hypothetical nuclear protein [Schizosaccharomyces pombe]
250.0 [0..176] [374..1]
gi|55730559 - gi|55730559|emb|CAH92001.1| hypothetical protein [Pongo abelii]
gi|55730559|emb|... - hypothetical protein [Pongo pygmaeus]
178.0 [0..209] [316..60]
gi|73954132 - gi|73954132|ref|XP_536456.2| PREDICTED: similar to Cofactor required for Sp1 transcriptional activat...
173.0 [0..209] [316..60]
gi|109487990, gi... - gi|109490586|ref|XP_001069084.1| PREDICTED: similar to Cofactor required for Sp1 transcriptional act...
172.0 [0..209] [356..60]
MED7_CANAL - Mediator of RNA polymerase II transcription subunit 7 OS=Candida albicans (strain SC5314 / ATCC MYA-...
MED7_CANAL - Mediator of RNA polymerase II transcription subunit 7 OS=Candida albicans GN=MED7 PE=3 SV=1
171.0 [0..224] [376..164]
MED7_DANRE - Mediator of RNA polymerase II transcription subunit 7 OS=Danio rerio GN=med7 PE=2 SV=1
166.0 [0..209] [317..60]
gi|47182712 - gi|47182712|emb|CAG13624.1| unnamed protein product [Tetraodon nigroviridis]
166.0 [0..209] [316..24]
MED7_ANOGA - Mediator of RNA polymerase II transcription subunit 7 OS=Anopheles gambiae GN=MED7 PE=3 SV=2
gi|55241950, gi|... - gi|58382667|ref|XP_312090.2| AGAP002823-PA [Anopheles gambiae str. PEST], gi|55241950|gb|EAA07749.3|...
164.0 [0..209] [314..62]
MED7_XENTR - Mediator of RNA polymerase II transcription subunit 7 OS=Xenopus tropicalis GN=med7 PE=2 SV=1
162.0 [0..163] [362..15]

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Predicted Domain #1
Region A:
Residues: [1-106]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEPNEGVQLF SAFPPPPPYY KLFTRENIEK VISNMEKEAK HEDDANTLQP KTEEEIESLA  60
   61 KLFKKPSCLT SGTYQMFGDT WRLDEAIPSL KEFGIPELYK DIKDGE

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.550 N/A N/A a.39.1 EF-hand
View Download 0.505 N/A N/A b.88.1 Mss4-like
View Download 0.285 N/A N/A a.47.2 t-snare proteins
View Download 0.277 N/A N/A a.47.2 t-snare proteins
View Download 0.273 N/A N/A d.58.56 Description not found.
View Download 0.271 N/A N/A a.2.17 Description not found.
View Download 0.251 N/A N/A d.58.56 Description not found.
View Download 0.225 N/A N/A g.36.1 Ferredoxin thioredoxin reductase (FTR), catalytic beta chain
View Download 0.207 N/A N/A c.78.2 Aspartate/glutamate racemase
View Download 0.200 N/A N/A d.95.2 Homing endonucleases

Predicted Domain #2
Region A:
Residues: [107-201]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DEIEVVEYDP KSNAIVGTSF TRVHDYDKNS PIENEKILED DQHTAMKEKD NESDKTMKDV  60
   61 EEKTEPSLKK EEEDIQMKEP LDSQDTGAVS ASSVN

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 4.13
Match: 1ykeA
Description: Structure of the mediator MED7/MED21 subcomplex
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [202-376]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EGFRADQKSK DGETSDLIKI PRRAYELRFL SRSLMLNFLE LLGIMAKAPE QFPSKVENIR  60
   61 VLLLNLHHLI NDYRPHQSRE SLIMLLEKQL KHEESQVELL RTHNRQMTET LEKYKSLDFN 120
  121 MEKEGDVIQQ LKSSIKKPLS GAEDEQKSRS MFSKNDEKLK KSLELMEDVI KRDLS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 26.221849
Match: 1ykeA
Description: Structure of the mediator MED7/MED21 subcomplex
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle