YRC Public Data Repository - Protein Structure Prediction

Protein:	prs1
Organism:	Schizosaccharomyces pombe
Length:	409 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for prs1.

Description	E-value	Query Range	Subject Range
gi\|224098594 - gi\|224098594\|ref\|XP_002187809.1\| PREDICTED: similar to phosphoribosyl pyrophosphate synthetase 1 iso... gi\|50745642 - gi\|50745642\|ref\|XP_420181.1\| PREDICTED: hypothetical protein [Gallus gallus] gi\|542151400\|ref... - PREDICTED: ribose-phosphate pyrophosphokinase 1 isoform X2 [Zonotrichia albicollis]	393.0	[0..1]	[343..1]
gi\|33303737 - gi\|33303737\|gb\|AAQ02382.1\| phosphoribosyl pyrophosphate synthetase 1 [synthetic construct]	392.0	[0..1]	[343..1]
gi\|62897899 - gi\|62897899\|dbj\|BAD96889.1\| phosphoribosyl pyrophosphate synthetase 1 variant [Homo sapiens]	389.0	[0..1]	[343..1]
gi\|57527447, gi\|... - gi\|57527447\|ref\|NP_001009694.1\| ribose-phosphate pyrophosphokinase I -like [Rattus norvegicus], gi\|5...	389.0	[0..1]	[343..1]
PRPS1_MOUSE - Ribose-phosphate pyrophosphokinase 1 OS=Mus musculus GN=Prps1 PE=1 SV=3	389.0	[0..1]	[343..1]
gi\|68372393, gi\|... - gi\|68372393\|ref\|XP_685452.1\| PREDICTED: similar to Ribose-phosphate pyrophosphokinase I -like isofor...	389.0	[0..1]	[343..1]
PRPS2_XENTR - Ribose-phosphate pyrophosphokinase 2 OS=Xenopus tropicalis GN=prps2 PE=2 SV=1	389.0	[0..1]	[343..1]
gi\|76659836 - gi\|76659836\|ref\|XP_617865.2\| PREDICTED: similar to Ribose-phosphate pyrophosphokinase II (Phosphorib...	388.0	[0..1]	[343..28]

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Predicted Domain #1

Region A:
Residues: [1-331]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKSATIIGGG SHPELLHLIS NRLGITPCDV SLKRFANGET SVEIRESVRD KDVFILQSGS  60
   61 STVNDSLMEL LIIISACKGG SAKRITAVMP YFPYSKQSKM RKYRDAITAR MVANLLTVAG 120
  121 VDHIITLDLH ASQMQGFFTR PVDNLYAEPN IAEWIRRNVD DWEEAVVVSK NPGGAKRVTS 180
  181 LADTLNLDFA LINTDRQRSS HFSQNFEDSI MDETEATETH VTNCSVYLDR PRIHTAKYLL 240
  241 GHIIDDEEII TTPASVCSED YAQEVNLYSQ GGCPSDDDEE ENIMSASIYA ERMITLVGDV 300
  301 NGKTALLIDD TIENPTAFIV ASEHLVKRCG A

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	109.0
Match:	2h06A
Description:	No description for 2h06A was found.

Predicted Domain #2

Region A:
Residues: [332-409]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KRVIVIGTHG IFQNKCLKDL QSCEYIEQIV VTNTYPIKPQ AVLECDKLTV IDISGVLAEA  60
   61 IRRTHNGESI SFLFKKAF

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	37.39794
Match:	1ecbA
Description:	Glutamine PRPP amidotransferase, C-terminal domain; Glutamine PRPP amidotransferase, N-terminal domain
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits