YRC Public Data Repository - Protein Structure Prediction

Protein:	SPBC4C3.03
Organism:	Schizosaccharomyces pombe
Length:	338 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPBC4C3.03.

Description	E-value	Query Range	Subject Range
gi\|119188085, gi... - gi\|90303435\|gb\|EAS33066.1\| hypothetical protein CIMG_04090 [Coccidioides immitis RS], gi\|119188085\|r...	243.0	[0..2]	[335..1]
gi\|49651244 - gi\|49651244\|emb\|CAG78181.1\| YALI0F13453p [Yarrowia lipolytica] gi\|50555932, gi\|... - gi\|50555932\|ref\|XP_505374.1\| YALI0F13453p [Yarrowia lipolytica], gi\|49651244\|emb\|CAG78181.1\| unnamed...	238.0	[0..2]	[336..3]
gi\|114188888, gi... - gi\|115438466\|ref\|XP_001218073.1\| homoserine kinase [Aspergillus terreus NIH2624], gi\|114188888\|gb\|EA...	236.0	[0..2]	[337..3]
KHSE_YEAST - Homoserine kinase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=THR1 PE=1 SV=4 THR1 - Homoserine kinase, conserved protein required for threonine biosynthesis; expression is regulated by...	235.0	[0..4]	[336..5]
KHSE_CANAL - Homoserine kinase OS=Candida albicans GN=THR1 PE=3 SV=2 gi\|238882477 - gi\|238882477\|gb\|EEQ46115.1\| homoserine kinase [Candida albicans WO-1] KHSE_CANAL - Homoserine kinase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=THR1 PE=3 SV=2	233.0	[0..1]	[337..3]
gi\|11611461, gi\|... - gi\|32406008\|ref\|XP_323617.1\| hypothetical protein ( (AL451109) probable homoserine kinase [Neurospor... gi\|85100999 - gi\|85100999\|ref\|XP_961067.1\| homoserine kinase [Neurospora crassa OR74A]	233.0	[0..1]	[335..7]
gi\|39961652, gi\|... - gi\|39961652\|ref\|XP_364705.1\| hypothetical protein MG09550.4 [Magnaporthe grisea 70-15], gb\|EAA53800....	232.0	[0..3]	[336..5]
gi\|238503446, gi... - gi\|238503446\|ref\|XP_002382956.1\| homoserine kinase [Aspergillus flavus NRRL3357], gi\|220690427\|gb\|EE... gi\|169765259 - gi\|169765259\|ref\|XP_001817101.1\| hypothetical protein [Aspergillus oryzae RIB40] gi\|83764955 - gi\|83764955\|dbj\|BAE55099.1\| unnamed protein product [Aspergillus oryzae]	231.0	[0..2]	[337..3]
gi\|49655812, gi\|... - gi\|50423127\|ref\|XP_460144.1\| hypothetical protein DEHA0E20405g [Debaryomyces hansenii CBS767], gi\|49... gi\|49655812 - gi\|49655812\|emb\|CAG88417.1\| DEHA2E19294p [Debaryomyces hansenii]	231.0	[0..1]	[337..3]

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Predicted Domain #1

Region A:
Residues: [1-338]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQKFQIKVPA SSANIGPGFD VLGMSLEEYM TLDVEVSTES GPCVLTYEGD GKEHVSLDVQ  60
   61 KNMITQTSLY VLRCNNISTF PYATKIHVIN PIPLGRGMGS SGSAAIAGVM LANEIAKLGL 120
  121 SKLQMMDYVL MIERHPDNVM ASMMGGFVGS FLRELSEEEK NAFSPSADDL LKNEALTLPP 180
  181 KSLGTFARLP WASELKAIVV IPEFHLATSK ARSVLPTSYG RTDVVYNLQR LALLTTALGQ 240
  241 TPINPHLVYE VMKDKVHQPY RASLIPGLQN ILATLNPDTQ PGLCGICLSG AGPTVLALAT 300
  301 GNFDEIAHAM LSIFEKHGVK CRYLVLSPAF DGATVKYF

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	52.69897
Match:	1wuuA
Description:	crystal structure of human galactokinase complexed with MgAMPPNP and galactose
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	0.836142537655721	bayes_pls_golite062009
structural constituent of ribosome	0.0246382239358082	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: