YRC Public Data Repository - Protein Structure Prediction

Protein:	hcs1
Organism:	Schizosaccharomyces pombe
Length:	447 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for hcs1.

Description	E-value	Query Range	Subject Range
HMCS2_RAT - Hydroxymethylglutaryl-CoA synthase, mitochondrial OS=Rattus norvegicus GN=Hmgcs2 PE=1 SV=1	389.0	[0..3]	[447..49]
gi\|21758044 - gi\|21758044\|dbj\|BAC05233.1\| unnamed protein product [Mus musculus] IPI:IPI00167251.... - Hypothetical protein FLJ40785	388.0	[0..3]	[447..49]
gi\|46134253, gi\|... - gi\|46134253\|ref\|XP_389442.1\| hypothetical protein FG09266.1 [Gibberella zeae PH-1], gi\|42554064\|gb\|E...	386.0	[0..1]	[446..1]
gi\|55587844 - gi\|55587844\|ref\|XP_513693.1\| PREDICTED: 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2 (mitochondr...	386.0	[0..3]	[447..49]
HMGCS2 - 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)	385.0	[0..3]	[447..49]
gi\|50925193, gi\|... - gi\|50925193\|gb\|AAH79694.1\| MGC80816 protein [Xenopus laevis], gi\|148224514\|ref\|NP_001087380.1\| MGC80...	385.0	[0..2]	[445..11]
gi\|109014698 - gi\|109014698\|ref\|XP_001114146.1\| PREDICTED: 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2 (mitoch...	385.0	[0..3]	[447..49]

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Predicted Domain #1

Region A:
Residues: [1-447]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSFDRKDIGI KGLVLYTPNQ YVEQAALEAH DGVSTGKYTI GLGLTKMAFV DDREDIYSFG  60
   61 LTALSQLIKR YQIDISKIGR LEVGTETIID KSKSVKSVLM QLFGDNHNVE GIDCVNACYG 120
  121 GVNALFNTID WIESSAWDGR DGIVVAGDIA LYAKGNARPT GGAGCVALLV GPNAPIVFEP 180
  181 GLRGTYMQHA YDFYKPDLTS EYPYVDGHFS LECYVKALDG AYANYNVRDV AKNGKSQGLG 240
  241 LDRFDYCIFH APTCKQVQKA YARLLYTDSA AEPSNPELEG VRELLSTLDA KKSLTDKALE 300
  301 KGLMAITKER FNKRVSPSVY APTNCGNMYT ASIFSCLTAL LSRVPADELK GKRVGAYSYG 360
  361 SGLAASFFSF VVKGDVSEIA KKTNLVNDLD NRHCLTPTQY EEAIELRHQA HLKKNFTPKG 420
  421 SIERLRSGTY YLTGIDDMFR RSYSVKP

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	104.0
Match:	2p8uA
Description:	No description for 2p8uA was found.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits