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View Structure Prediction Details

Protein: cdc15
Organism: Schizosaccharomyces pombe
Length: 927 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for cdc15.

Description E-value Query
Range
Subject
Range
gi|109732781 - gi|109732781|gb|AAI16186.1| ITSN1 protein [Homo sapiens]
237.0 [0..57] [925..331]
gi|114683967 - gi|114683967|ref|XP_531442.2| PREDICTED: intersectin 1 isoform 5 [Pan troglodytes]
236.0 [0..57] [925..331]
gi|74001183 - gi|74001183|ref|XP_857836.1| PREDICTED: similar to intersectin 1 isoform ITSN-l isoform 9 [Canis fam...
235.0 [0..57] [925..331]
ITN1_MOUSE, ITSN... - Intersectin-1 OS=Mus musculus GN=Itsn1 PE=1 SV=1, (Q9Z0R4) Intersectin 1 (EH and SH3 domains protein...
229.0 [0..59] [925..335]
gi|149059858, gi... - gi|62657647|ref|XP_573259.1| PREDICTED: similar to Intersectin-1 (EH and SH3 domains protein 1) [Rat...
225.0 [0..59] [925..335]

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Predicted Domain #1
Region A:
Residues: [1-302]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEVNGVSQSE AAPYVTKSSV KFRDNFWGSE DAGMDALMSR TKSSLSVLES IDEFYAKRAS  60
   61 IEREYASKLQ ELAASSADIP EVGSTLNNIL SMRTETGSMA KAHEEVSQQI NTELRNKIRE 120
  121 YIDQTEQQKV VAANAIEELY QKKTALEIDL SEKKDAYEYS CNKLNSYMRQ TKKMTGRELD 180
  181 KYNLKIRQAA LAVKKMDAEY RETNELLLTV TREWIDRWTE VCDAFQHIEE YRLEFLKTNM 240
  241 WAYANIISTA CVKDDESCEK IRLTLENTNI DEDITQMIQN EGTGTTIPPL PEFNDYFKEN 300
  301 GL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 36.30103
Match: 2v0oA
Description: No description for 2v0oA was found.

Predicted Domain #2
Region A:
Residues: [303-417]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NYDIDQLISK APSYPYSSSR PSASASLASS PTRSAFRPKT SETVSSEVVS SPPTSPLHSP  60
   61 VKPVSNEQVE QVTEVELSIP VPSIQEAESQ KPVLTGSSMR RPSVTSPTFE VAARP

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [418-636]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LTSMDVRSSH NAETEVQAIP AATDISPEVK EGKNSENAIT KDNDDIILSS QLQPTATGSR  60
   61 SSRLSFSRHG HGSQTSLGSI KRKSIMERMG RPTSPFMGSS FSNMGSRSTS PTKEGFASNQ 120
  121 HATGASVQSD ELEDIDPRAN VVLNVGPNML SVGEAPVEST SKEEDKDVPD PIANAMAELS 180
  181 SSMRRRQSTS VDDEAPVSLS KTSSSTRLNG LGYHSRNTS

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [637-696]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IASDIDGVPK KSTLGAPPAA HTSAQMQRMS NSFASQTKQV FGEQRTENSA RESLRHSRSN  60
   61 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [697-927]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSRSPSPMLS RRSSTLRPSF ERSASSLSVR QSDVVSPAPS TRARGQSVSG QQRPSSSMSL  60
   61 YGEYNKSQPQ LSMQRSVSPN PLGPNRRSSS VLQSQKSTSS NTSNRNNGGY SGSRPSSEMG 120
  121 HRYGSMSGRS MRQVSQRSTS RARSPEPTNR NSVQSKNVDP RATFTAEGEP ILGYVIALYD 180
  181 YQAQIPEEIS FQKGDTLMVL RTQEDGWWDG EIINVPNSKR GLFPSNFVQT V

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 18.154902
Match: 1ycsB
Description: 53BP2
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle