YRC Public Data Repository - Protein Structure Prediction

Protein:	SPAC186.03
Organism:	Schizosaccharomyces pombe
Length:	360 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPAC186.03.

Description	E-value	Query Range	Subject Range
ASPG3_SCHPO - Probable L-asparaginase 3 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=SPBPB21E7.09 PE=... SPBPB21E7.09 - L-asparaginase	425.0	[0..1]	[360..1]
gi\|28900229, gi\|... - gi\|28900229\|ref\|NP_799884.1\| L-asparaginase II [Vibrio parahaemolyticus RIMD 2210633], gi\|28808540\|d... gi\|28808540 - gi\|28808540\|dbj\|BAC61717.1\| periplasmic L-asparaginase II [Vibrio parahaemolyticus RIMD 2210633]	407.0	[0..29]	[357..18]
gi\|75857807, gi\|... - gi\|75857807\|ref\|ZP_00765419.1\| COG0252: L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit...	406.0	[0..28]	[357..17]
gi\|32266161, gi\|... - gi\|32266161\|ref\|NP_860193.1\| L-asparaginase [Helicobacter hepaticus ATCC 51449], gi\|32262211\|gb\|AAP7...	403.0	[0..22]	[357..34]
gi\|91224109, gi\|... - gi\|91224109\|ref\|ZP_01259372.1\| periplasmic L-asparaginase II [Vibrio alginolyticus 12G01], gi\|911910...	402.0	[0..28]	[357..17]
gi\|90324982, gi\|... - gi\|90413920\|ref\|ZP_01221905.1\| putative periplasmic L-asparaginase II [Photobacterium profundum 3TCK...	401.0	[0..29]	[357..18]
gi\|54302853, gi\|... - gi\|54302853\|ref\|YP_132846.1\| L-asparaginase II [Photobacterium profundum SS9], gi\|46916277\|emb\|CAG23...	399.0	[0..29]	[357..18]
gi\|59480235, gi\|... - gi\|59712134\|ref\|YP_204910.1\| L-asparaginase II [Vibrio fischeri ES114], gi\|59480235\|gb\|AAW86022.1\| p...	395.0	[0..30]	[357..18]
gi\|89047962, gi\|... - gi\|89076330\|ref\|ZP_01162667.1\| periplasmic L-asparaginase II [Photobacterium sp. SKA34], gi\|89047962...	392.0	[0..29]	[357..19]

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Predicted Domain #1

Region A:
Residues: [1-360]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MWRSIISFLF FSVALCQPFL FQKRSSNISD FISFNASLPN VTIFAMGGTI AGYASSSTET  60
   61 VDYAAGSVGI ATLVDAVPAI KNFSNIRGVQ VTNVGSEELT PANVLNLTQL ILAEVAKPDV 120
  121 HGIVVTHGTD SLEETAMFLD MTVNTTKPIV VVGAMRPSTA ISADGPMNLL NAVVVAASNR 180
  181 SIGRGTMILL NDRIGSAFYT TKTNGNMLDT FKSYEAGFLG MILDQRPHFF YSPATPTGKV 240
  241 HFDVSNTTEL PAVEILYGYQ GLNPNLAKAA VDLGAKGLVL AGMGAASWTD PGNEVIDGLI 300
  301 SNQSIPVVYS HRTMDGFSDY YYNGIPSYFQ NPQKARYMLM LSINAGYSIQ NITDIFSLEY 360
  361

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	105.0
Match:	1hfjA
Description:	Asparaginase type II
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
asparaginase activity	5.31552786314061	bayes_pls_golite062009
hydrolase activity	4.24082880889802	bayes_pls_golite062009
catalytic activity	1.35076351157997	bayes_pls_golite062009
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	0.739997194025722	bayes_pls_golite062009
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	0.584091474722373	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: