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View Structure Prediction Details

Protein: Grip84-PA
Organism: Drosophila melanogaster
Length: 926 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Grip84-PA.

Description E-value Query
Range
Subject
Range
Grip84-PB - The gene gamma-tubulin ring protein 84 is referred to in FlyBase by the symbol Dmel\Grip84 (CG3917, ...
659.0 [0..76] [926..2]

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Predicted Domain #1
Region A:
Residues: [1-307]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSKPHALRGV LANLISESQS PLTPESIIRE FRATSDRRLP ACDLIKVLVS ISEKRPNFAE  60
   61 VTKEISHILQ NKDPMYALLV FVERYSECKP VSESSSSTSL SAMGLPHGNK TSDVNSAAGS 120
  121 VPTTLAIAST STILTTSQNV SGSTRLSLTQ SQDFPTSTPV NCKKATESDT TPVVFVRRGP 180
  181 MDRNRGAGKD ERNDLSVIKE RVLNAVSDQS LSGYRSVTNK TGNSPKSMPN DLVTLTDVPD 240
  241 EYRTHLLWEY YKVDGDKVPR AEIAAMPLLS QESMLLDELL HCLTGIRESL LVPQKPIISA 300
  301 VGLAKYD

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 2.06
Match: 1h1kI
Description: THE BLUETONGUE VIRUS (BTV) CORE BINDS DSRNA
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [308-467]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TDFDIHTHLD RSLTHQVREI LPLASYFMGV QKIIAATDGL GQVMNSLNEA LQELTHDFYL  60
   61 IIVQAEQELR HNRLTLQKLL YYLQPTMWVM HEVWSSLVII QLSDSRDAEV LTYLHERIKR 120
  121 LEGNKDAQQL IIGLVRKAAK PYMRMLQMWI QKGVIVDRHR 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [468-664]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EFLVVDNEVI HRDELPEHYS DDYWERRYTL RDEQIPSFLA KYSDKILRTG KYLNVIRQCG  60
   61 KRVMPTQEMN LEFDPTSERH VSVINDAYYF AARMLLDVLL TENDLMGHLQ SVKRYLLLNQ 120
  121 GDFTMQFMDA CEDELTKNVD HVLPMTLENL LGLTLRISSA RNDPYKDDLH CELLPYDLVT 180
  181 QMSKIMKKEE NWQAQPR

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [665-769]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LDLSGLECFA FTYEVKWPCS LVLNHISISK YQMLFRQLFY CKHVERQLCK IWKENSIARQ  60
   61 FEPQAASLYR AAFTLRQRMM NAIQNLEYYM MIEIIEPNWH IFIEK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.855 0.034 microtubule nucleation a.24.14 FAT domain of focal adhesion kinase

Predicted Domain #5
Region A:
Residues: [770-926]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKTVENVDNV LRLHQDFLDS CLKNCMLTES SHLNRSIFKL CKICLKYCEF IQITQRYFQD  60
   61 AELRSMVRDS ADSSESEQES LHCPQIETPL DPTDTFSERV RRFDLEFTQL LISFLKQINS 120
  121 MAKKNTADCF MNLVHRINFN AFYTDQMDKM CVEDAIG

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle