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View Structure Prediction Details

Protein: CG8945-PC
Organism: Drosophila melanogaster
Length: 1430 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CG8945-PC.

Description E-value Query
Range
Subject
Range
gi|73975552 - gi|73975552|ref|XP_532425.2| PREDICTED: similar to Carboxypeptidase A2 precursor isoform 1 [Canis fa...
532.0 [0..958] [1430..1]

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Predicted Domain #1
Region A:
Residues: [1-216]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVTGLPVVLL IVVMVVDVVH RTGAIDFGYH PSAEESDSLV RQSWGRDLLQ RRVQDRRFVP  60
   61 RYQHQTSIRF EPPELDFQLF DEDQDQAPSQ PYVFESVEES QPGSTIFDQF HVQSELLEIK 120
  121 EPNPSRKPQT KPQSAGNGTT FPIYFTHPTT GIVYAISQVG VGHNPNGIPT QSRNDSNAIA 180
  181 IYVTKAQYDA DMESLRRQYE QQCLPIPPGT VISTLN

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [217-426]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PVHHGGTTAR PQIIRLKKPK NPITKPSNKL PKPNYRPPPV MVTSGPIDHV SDQLLKLPHR  60
   61 TGSTTRSTTT TTSTTSRPNT RRKKRKKIPK NKTKVIKKRP GYGANNTRGP QGSLPIILGK 120
  121 RPSTTTTTTT SRPPPAYTQL EKPHMPQATL PTSNVFSQHL LRSDLEPAEE SETLEEQEPL 180
  181 QSDEQLNLRI RRSVEDVRRE KRRGPLHAKK 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [427-489]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RNSSLKALIK KSVLKNAVKR ARLLKNQGEM DSSRTQHRRS RRSLYSIKNG EIEKSIKTEK  60
   61 ATK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [490-902]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VPSEEAEKEV TADSTKRSQK VVSKESKTIL SRGNPNVVAA RRVSTPKRRS PKGSSGRRKT  60
   61 KQQTPPSTQK KEKNSGGVLH IPTALHLLHR NHSQDEVPKV PLNANQKKKR KVKERKRGRP 120
  121 QLPSFDIFEL MSDGDYEDEG EEEEEEQDDD EDYYFEDEHK DEDKNKPNES SSTEVGQSDL 180
  181 KEDSSSAEEG ADFGAMVEEE TTTTATISSS EELDATSSTK NSMAKKKIRI KRRPVDSDED 240
  241 YDDDEDSGIA GFFRMIFYPV QVAMSRLMDG FGTPDEEEDK EPATQPVSKY PSYTLYHSAH 300
  301 SNEAYAEPDD EDSEDDEDSS SLGSWFGSWF GLQRRTKKIG STTTTMPVPL PPPTKAPPSW 360
  361 LESWFGFGST TEADAEDDYD KWFSSWFDSR PKRKFRRRST TSTSTTSTTT TTH

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 13.69897
Match: 1i84S
Description: Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

Predicted Domain #5
Region A:
Residues: [903-972]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TPSAAAAQVP ILTIVDPLRN PQNWIGILAH HIVNSTGSAI STSTSNPLLQ ALATRMTTRG  60
   61 TTSTTTTTSR 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #6
Region A:
Residues: [973-1430]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PDVPRRISYD KYQIWRLKPQ DEEQVRALEE FKKGEDGVKL QWLKGPSLRG LTDVLVPPKM  60
   61 LVDFQGTLNY EGIAHEVLIF DVGKAIAYEL TKEDYLQTTR PSKPRPTAPP PMTWNRYHNH 120
  121 DEIVKYLETV RMRHPQLVEL IHIGRSFEGR PLIVVKIESK QTAAAANNDG LHTIKRPKRK 180
  181 RKSGQANAVF VEAGAQGLAW IGPAAATWMI AELLRLMKTN KSNEDVEFIR NTTWYIMPVL 240
  241 NPDGYAYSHE YDRFWKKSRS QHQTPPPSGL LDSAMTWLQQ KRGPDKVCYG VDLDRNWLYH 300
  301 WGKRGSSKAP CNEFYAGPAP FSEPETKAVS EFLMDYRTQI KLYISLQAYG QVISYPVKAN 360
  361 STFNSERLDD FLDVAMVGTD GLRKKGSKSR YKVDASNDLI EQRSGCADAF AAYEIGIPFS 420
  421 YTLQLADNGV HGYLLPSSAI EPTARDAFEI ISGMLDYI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 147.0
Match: 2boaA
Description: Human procarboxypeptidase A4.
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle