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View Structure Prediction Details

Protein: mbt-PA
Organism: Drosophila melanogaster
Length: 639 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for mbt-PA.

Description E-value Query
Range
Subject
Range
gi|4104087 - gi|4104087|gb|AAD01935.1| Ste20 serine/threonine protein kinase homolog [Drosophila melanogaster]
417.0 [0..1] [639..1]

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Predicted Domain #1
Region A:
Residues: [1-86]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFSKKKKKPL ISMPSNFEHR VHTGFDKREN KYVGLPLQWA SIVGNNQILK SSNRPLPLVD  60
   61 PSEITPTEIL DLKTIVRPHH NNNKAD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 20.30103
Match: 1f3mA
Description: pak1 autoregulatory domain
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [87-334]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TTSLNSSSTM MMGSMAPMNP MAPGAHPMMS HGPGMMMPPE TGGIVLPKTS HVARSNSLRS  60
   61 SSPPRVRRVA NVPPSVPEEE GPPAAGTPGV GGASSGGFKP PGAHPSLLYN SQHAHANGAT 120
  121 GPLAVRTDQT NLQQYRSNLA PPSGGSMPQQ QQTSPVGSVA SGTRSNHSHT NNGNSGGSYP 180
  181 PMYPTSHQQQ QQQQQQAKQG GDQNQNPLHP HAHPHPHHHQ HLAKSASRAS SSSGGASSAA 240
  241 QQASGASG

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [335-639]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GAAGQPKQDQ RLTHEQFRAA LQMVVSAGDP RENLDHFNKI GEGSTGTVCI ATDKSTGRQV  60
   61 AVKKMDLRKQ QRRELLFNEV VIMRDYHHPN IVETYSSFLV NDELWVVMEY LEGGALTDIV 120
  121 THSRMDEEQI ATVCKQCLKA LAYLHSQGVI HRDIKSDSIL LAADGRVKLS DFGFCAQVSQ 180
  181 ELPKRKSLVG TPYWMSPEVI SRLPYGPEVD IWSLGIMVIE MVDGEPPFFN EPPLQAMRRI 240
  241 RDMQPPNLKN AHKVSPRLQS FLDRMLVRDP AQRATAAELL AHPFLRQAGP PSLLVPLMRN 300
  301 ARHHP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 75.522879
Match: 2f57A
Description: Crystal Structure Of The Human P21-Activated Kinase 5
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle