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View Structure Prediction Details

Protein: disco-PA, disco-PB
Organism: Drosophila melanogaster
Length: 568 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for disco-PA, disco-PB.

Description E-value Query
Range
Subject
Range
gi|76651068 - gi|76651068|ref|XP_887912.1| PREDICTED: similar to zinc finger protein 192 isoform 5 [Bos taurus]
686.0 [0..1] [556..375]

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Predicted Domain #1
Region A:
Residues: [1-185]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEHIMNPFMS PAYLLGHGPH SHQHVHSHLP SHPQPNAASP ASSPGGSSGS GSGSAAGSGT  60
   61 GSGSSLKPRR WGSPPINLAG QFINPATGKK RVQCSICFKT FCDKGALKIH FSAVHLREMH 120
  121 KCTVEGCNMV FSSRRSRNRH SANPNPKLHS PHIRRKISPH DGRTAQQFPV FSPGTAAAAA 180
  181 AVAGR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 52.522879
Match: 2i13A
Description: No description for 2i13A was found.

Predicted Domain #2
Region A:
Residues: [186-392]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LPVAFPGLLP PPPPHHGHHP YVMFGGQAGL HGLGLLSTGC QDPDSGSVDN EQDADPEDDN  60
   61 DFVYVDMQAN SSSPAASSED QEEHERDNEQ DEEMHCSLSL ASSSSIAADE ERAADQPLDF 120
  121 SLHKRRKSEQ DREQEQEQEQ EREREAEKEQ EQDVESDKEH EPEQEHELER EKRSPSDAFS 180
  181 MDQLLGKRKR HDSTASSSAC STAAASS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 16.69897
Match: 1a1iA
Description: ZIF268
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [393-447]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ASSSSASASA NPPQTSIKMD LDPDSDSAYM TSRRQMLPLP VLDLEEHHHL RLLQT

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [448-568]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QMFAAAAAAA ATSQAPPTAF LPAGSPVDLA KDSPPMWSLL SEMYRSMLLK TQHQQYNHHH  60
   61 QLQQQHQQEQ HHHLTLSHHH QEQHHHLGHH HMGHHHHHHH QHHQQQPQQQ SPAATNAPIS 120
  121 V

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 20.522879
Match: 1meyC
Description: Designed zinc finger protein
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle