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View Structure Prediction Details

Protein: acj6-PA
Organism: Drosophila melanogaster
Length: 396 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for acj6-PA.

Description E-value Query
Range
Subject
Range
acj6-PD - The gene abnormal chemosensory jump 6 is referred to in FlyBase by the symbol Dmel\acj6 (CG9151, FBg...
138.0 [0..1] [396..1]

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Predicted Domain #1
Region A:
Residues: [1-203]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTMSMYSTTD KMKMSAPSCF PGRYSPSYRS SEQMRRCMPN PSIHISSSCD SLESRLLEDA  60
   61 SLLCNSWSAR QNGDIFAGIN DGILSRAEAL AAVDIQKHQA QHVHSQMPSQ IKHDVMYHHH 120
  121 SMSGPPQRPL QENPFSRQMH HSMDQLDMLD PTGSMTTLAP ISESPLTPTH QHLHGSYHSM 180
  181 NHMMSHHHPG TLSGHTGGHH GHS

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [204-396]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AVHHPVITAA VAAAGLHPDT DTDPRELEAF AERFKQRRIK LGVTQADVGK ALANLKLPGV  60
   61 GALSQSTICR FESLTLSHNN MIALKPILQA WLEEAEAQAK NKRRDPDAPS VLPAGEKKRK 120
  121 RTSIAAPEKR SLEAYFAVQP RPSGEKIAAI AEKLDLKKNV VRVWFCNQRQ KQKRIVSSVT 180
  181 PSMTGHGSAG FGY

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 23.39794
Match: 1o4xA
Description: TERNARY COMPLEX OF THE DNA BINDING DOMAINS OF THE OCT1 AND SOX2 TRANSCRIPTION FACTORS WITH A 19MER OLIGONUCLEOTIDE FROM THE HOXB1 REGULATORY ELEMENT
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
DNA binding 5.51228466689923 bayes_pls_golite062009
nucleic acid binding 5.37468811865033 bayes_pls_golite062009
transcription regulator activity 5.05236457497789 bayes_pls_golite062009
transcription factor activity 3.89464979825638 bayes_pls_golite062009
binding 3.66501723413351 bayes_pls_golite062009
RNA polymerase II transcription factor activity 3.22754992035091 bayes_pls_golite062009
sequence-specific DNA binding 2.15092997144587 bayes_pls_golite062009
transcription activator activity 1.82965737603728 bayes_pls_golite062009
transcription repressor activity 1.75958281319075 bayes_pls_golite062009
protein binding 1.55649304400241 bayes_pls_golite062009
transcription factor binding 1.02788976342343 bayes_pls_golite062009
specific RNA polymerase II transcription factor activity 0.92393807212912 bayes_pls_golite062009
transcription cofactor activity 0.8718993114781 bayes_pls_golite062009
chromatin binding 0.62573870961765 bayes_pls_golite062009
catalytic activity 0.00446472034106909 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle