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View Structure Prediction Details

Protein: rab3-GEF-PA
Organism: Drosophila melanogaster
Length: 2075 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for rab3-GEF-PA.

Description E-value Query
Range
Subject
Range
gi|58381320, gi|... - gi|58381320|ref|XP_311160.2| ENSANGP00000001501 [Anopheles gambiae str. PEST], gi|55242962|gb|EAA068...
2073.0 [0..2] [1773..1]

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Predicted Domain #1
Region A:
Residues: [1-182]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSDQQKASLC PRLVDYMAIV GAHTTPPMPK GLQGLKAPPV QVPDLLRRYP PSDHADFPLP  60
   61 LDMVYFCQPE GCTSVGPRRT GSAIRDMTSF VFALTDKDSG KTRYGICVNF YRPIERPSSA 120
  121 AGSAGAGNDR PGNGGPGGHG GGAGGGAGGG GRAPSDSDRE LTSRRDSDQQ RLHSHHSHHQ 180
  181 PH

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 50.958607
Match: PF03456.9
Description: No description for PF03456.9 was found.

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [183-263]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HPSASPAVPK LGLMAPSADS ESGGSHSPSP RASRKRTKLR NQSLTSLCII SHHPFFTTFR  60
   61 ECLFILKKLI DACNESSSPK R

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [264-459]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VGASQKINRD NVWTVLTGHV SDATPSIVLH DVREIETWIL RLLSTPVPVP GSTRVEVEVL  60
   61 SPTVHEPLLF ALPDHTRFSL VDFPLHLPLE LLGVETCLKV WTLIMQENKV LFQSRDYNAL 120
  121 SMSVMAFVTM LYPLEYMFPV IPLLPTCLSC AEQLLLAPTP FVIGVPASFL VYKKNFRLPD 180
  181 DIWVVDLDST KLTPPT

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [460-526]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GGYEEIPPLP EPEGTILKNH LKQVSPKALS LNSLRLPLQT PPHSAQASQR NSMSAQGTIS  60
   61 SRQPSPM

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [527-636]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NSPALNPFVY GTDVDSVDVA TRVAMVRFFN AQNTLANFAE HTRTLRLYPR PVVAFQINSF  60
   61 LRSRPRASQF LNQFARTQAV EFLAEWSLTP TNVAFLRVQT GVMDPMQVGD 

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 26.142668
Match: PF03455.10
Description: No description for PF03455.10 was found.

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #6
Region A:
Residues: [637-742]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KPKWFAHALT PIRFSVWDDG SSLNGALRSL KQLECQPTDE SGSDSEGADS SSSSYSSLSD  60
   61 FVSEMASSDL SPSLHDVFGS YNRPHVVPQT LSSNLDPALV YHPPSK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #7
Region A:
Residues: [743-945]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LQYPEGIADA VASKEEEDEE RADSPVSSSS SRSDLSSPSF NRDSEFDFQP KGGQTLGSTT  60
   61 VGSGAAAPSF ELATPLAMRL EATIKMASIE QESDTVSTAT GKTIAAGSKL QRHPSDSESR 120
  121 PEKKIPPPLT PPVKQPGVSN ILARTGSSGS SSSSPGRQSS QSSLFENFAS HAKELVRETT 180
  181 RQSSQEGLLA HVDKHALDED LDD

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #8
Region A:
Residues: [946-1040]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KMRHTFEKFT LHAKKAAGEA SKQALEVSKQ AAGVSKNTLE DLTYVGKSTL GDLTKTAKEA  60
   61 ATKKGIIKIE EHSAGGAGPP PKSPGSQLAT HKQVQ

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #9
Region A:
Residues: [1041-1258]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QSGGQGGGNN FFSAIGTDFN GLASSTSTMF SGMFGKKSQQ KQVPVQQKQP NVSAGKAKSG  60
   61 INFDPFPGRK GLVERTPLIK HSGPRQTQEE LTRQQNQERS HSNAENQTFL KDVTNQVLAG 120
  121 EGVGWLKLNR FKKLMEDESY RTLVLSKLNK TLDKKIAPDD HIDDVCVTKP VWKGMLKCIQ 180
  181 AIAGGLDVTF ANFGLGGMAS VFQLMEVAHT HYWSKEIN

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #10
Region A:
Residues: [1259-1357]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EGSDMSSSLL SSHAASPMGS RENLRSPSSP NGSHSALGSE WASPQESRKS STQLAHGGPG  60
   61 GSHSGAPINR RLSSADSQDG QSTTEMFKDM LSQKRSALK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #11
Region A:
Residues: [1358-1426]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NMLTSFDSDA AGSTGALSVV SLGVRLPSSC RSTVSDTEYE NTTTSKDSKK SSGNLWSGKS  60
   61 TLSAGFRYT

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #12
Region A:
Residues: [1427-1671]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GGHLINTSSS PSPDSPRVYL FEGLLGKDRL NLWNQMQFWE DAFLDAVSQE RDMIGMDQGP  60
   61 IEMMERYKSL SESERKRLEH DEDRLLSTML YNLTAILVML NVAKDEIRRK IRRLLGKSHI 120
  121 GLVYSQEVHN VVDQINNLNG NDIDLKPLGS RLLHRQSFTV HQGTDVNGPL RFMEVRDDGL 180
  181 VLRSVDGTIV ERWWYERLVN MTYSPKTKLL CLWRRNGGQT QLHKYYTRKC KELYNCIKEA 240
  241 MERGG

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #13
Region A:
Residues: [1672-2075]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TPTNVPELGG EFPVQDMNTG EGGLLQVCLE GVGLLFSNSK FFVRLDHIRK CFTQKGGIFV  60
   61 LEEYNPKTRN LIQRKYQSSM SDQICYSVLC VFSYVAAGQD QKKNPVVITP QIQDIHAQQK 120
  121 QKHQQQQQHQ QPQQQQQPHQ TTTQQNQPTA VASAVPTTTA PAGQVNPNRM TAKSQAGSIS 180
  181 IRHTVPMQKP TITMSTVQPQ ARMPAQVATA SVPVTVPVPP TPAPPTSNPA KLPQLPPRVP 240
  241 SQPSTESLAS ISSPPPKLRT PMSAPPGPPP AIPPRTGAIS RSGSVPAARS FVRQASANST 300
  301 PPQYTPQPPP PFVIPKRHSG LARASTLSSS TSPSMSSSSA SNHPGHSQSQ QRASHGSVAA 360
  361 VLQSMPEAEP GYGSGSGSIS GSSSGSGSAS GSIASASPQA HRKH

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 8.69897
Match: 1y0fA
Description: No description for 1y0fA was found.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle