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View Structure Prediction Details

Protein: inaE-PA
Organism: Drosophila melanogaster
Length: 644 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for inaE-PA.

Description E-value Query
Range
Subject
Range
inaE-PD - The gene inactivation no afterpotential E is referred to in FlyBase by the symbol Dmel\inaE (CG33174...
682.0 [0..1] [644..1]

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Predicted Domain #1
Region A:
Residues: [1-96]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPGLVVFRRR WSVGSDDLVV PGAFLLTIHF ICFVIVSVSL VIFEYNTRIL SVKLLFYHLI  60
   61 GYLLILFFSI CVEIGICVIS MRGSILDAEA RTSINI

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [97-324]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 WIYLKSLVIL FDIAWLAVGS VWLGHYYTTA PIDDPKKVYI AIIICNWALV VITLITIWCT  60
   61 FDAAGRSWVK MKKYQRSMRE TESRFNYKRS NSMNRNWRQR KVMRAYQDSW DHRCRLLFCC 120
  121 MGSSERNRNS FTDIARLLSD FFRELDVVPS DVVAGLVLLR KFQRLEREAI VRQRKNGTYE 180
  181 FLSGVPITER TQFLALNDAK NYDFFQTVIH YMYFAQGAYG WPMYVIIN

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [325-644]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RSKMWHLVPE LKCFGCCCGT SDDTEVIQDN CCLCNYAALK KTLQLGDIDI VYATYHVDVG  60
   61 ETPFFVAIDY THRAVVISIR GTLSMKDILT DLNAEGEVLP LQPPRDDWLG HKGMVQAAIY 120
  121 IRNKLQEENL IERALQRNPD RQTHTFDLVL VGHSLGAGTA AILAILLKPE HPTLQCFSYS 180
  181 PPGGLLSMPA VEYSKSFITS VVLGKDVVPR IGLNQMEALR ADLINAIQRS VDPKWKTISC 240
  241 SVICCGCGPE PTSVVNMSGQ DTHINQYQEE RGTARSTSAH PTDSSIALTL HQPLYPPGRI 300
  301 IHIVRHHPKP DEQKYDSGWR 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 50.0
Match: 1dt3A
Description: Triacylglycerol lipase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
catalytic activity 0.866238607554457 bayes_pls_golite062009
hydrolase activity 0.52702612560045 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle