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View Structure Prediction Details

Protein: inaE-PD
Organism: Drosophila melanogaster
Length: 737 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for inaE-PD.

Description E-value Query
Range
Subject
Range
gi|20521123 - gi|20521123|dbj|BAA31634.2| KIAA0659 protein [Homo sapiens]
698.0 [0..1] [737..8]

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Predicted Domain #1
Region A:
Residues: [1-125]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPGLVVFRRR WSVGSDDLVV PGAFLLTIHF ICFVIVSVSL VIFEYNTRIL SVKLLFYHLI  60
   61 GYLLILFFSI CVEIGICVIS MRGSILDAEA RTSINIWIYL KSLVILFDIA WLAVGSVWLG 120
  121 HYYTT

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [126-325]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 APIDDPKKVY IAIIICNWAL VVITLITIWC TFDAAGRSWV KMKKYQRSMR ETESRFNYKR  60
   61 SNSMNRNWRQ RKVMRAYQDS WDHRCRLLFC CMGSSERNRN SFTDIARLLS DFFRELDVVP 120
  121 SDVVAGLVLL RKFQRLEREA IVRQRKNGTY EFLSGVPITE RTQFLALNDA KNYDFFQTVI 180
  181 HYMYFAQGAY GWPMYVIINR 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [326-586]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SKMWHLVPEL KCFGCCCGTS DDTEVIQDNC CLCNYAALKK TLQLGDIDIV YATYHVDVGE  60
   61 TPFFVAIDYT HRAVVISIRG TLSMKDILTD LNAEGEVLPL QPPRDDWLGH KGMVQAAIYI 120
  121 RNKLQEENLI ERALQRNPDR QTHTFDLVLV GHSLGAGTAA ILAILLKPEH PTLQCFSYSP 180
  181 PGGLLSMPAV EYSKSFITSV VLGKDVVPRI GLNQMEALRA DLINAIQRSV DPKWKTISCS 240
  241 VICCGCGPEP TSVVNMSGQD T

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 49.0
Match: 1dt3A
Description: Triacylglycerol lipase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
catalytic activity 0.866238607554457 bayes_pls_golite062009
hydrolase activity 0.52702612560045 bayes_pls_golite062009

Predicted Domain #4
Region A:
Residues: [587-737]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HINQYQEERG TARSTSAHPT DSSIALTLHQ PLYPPGRIIH IVRHHPKPDE QKYDSGWRNV  60
   61 LKNREPVYQA IWADSTDFDE VLISPVMLQD HMPDKVLAAL KKVVSCRDRT VKACTTRRRN 120
  121 DNTTITTTTT VTTTTTTTQN TDTRYSRPPS I

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
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