YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: tomosyn-PD, tomo...
Organism: Drosophila melanogaster
Length: 1470 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for tomosyn-PD, tomo....

Description E-value Query
Range
Subject
Range
tomosyn-PF, tomo... - The gene tomosyn is referred to in FlyBase by the symbol Dmel\tomosyn (CG17762, FBgn0030412). It is ...
803.0 [0..1] [1470..1]

Back

Predicted Domain #1
Region A:
Residues: [1-549]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKKFTFKGVL DGFRQSVQPQ ATRQEQEIQE QLKADHFTLK KTFRHGFPYS PTSFAFDPVQ  60
   61 KLLAIGDKSG YIRILGRPGV DAHAKHEGES ECAVLFAQFL VNEGALVTVT ADDTIHLWSI 120
  121 RQKTPRIVQS LKFQRERVTC IHLPVGSKWL YVGTEKGNIH VVHIDTFALS GYIINWNKAI 180
  181 EVVRTSHPGA VIALCDNPLD ANKLLIAFEC GLLVLWDLKA KCAELRWQAA EAVKSLAWHY 240
  241 EGKYFVSSHT DGSICSWPTK PQAKPQSQVC PHAKINKDGN AEKCKPIYKV DLKSSATGET 300
  301 FTIFSGGMPS EKGSKSNCIT VMVGKATTVL EMEHAVCDFI TLCENPWPCE TQEPYAIAVL 360
  361 LQYDLVLIDL LTPGFPCFES PYPMDLHESP VTCCTYLTDC PSDLVPAFYS VGRTTTSKKS 420
  421 CFSEREWPIS GGEWSPASCS YSEIVITGHQ DGSLKFWDSG AGTLQILYKL KTAKMFEKPR 480
  481 SHVAHSHPES DNPLAVHLIF LCSESRRLCV AGAMGQVMLF KFRKVESTSE VLVLEIPILY 540
  541 ENFDDIYGT

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 58.0
Match: 1nr0A
Description: Actin interacting protein 1
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [550-722]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SPECDFLTGH QVQKAESSDS DKTAECSLKV RNGAQRKPPG FQSQLVCLTT GPNRRNVQVT  60
   61 SLCISSSYGL MAYGTEYGLV IIDIIQKICL LSVACPDLYG AHDPYSRTPK SPKRIENKEE 120
  121 QSRSPSSDQI NGSGVATAAP QQQQQQQQQL QQSQQQQQQQ LQQQQQQQQQ QQQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 4.69897
Match: 2d5lA
Description: No description for 2d5lA was found.

Predicted Domain #3
Region A:
Residues: [723-864]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QQQQQQQSLG GDPGDHATST SAGAATLAGS SIYGADDAGA GVASGGVGVG GISSAISGGF  60
   61 GGAAEPQQQQ QVSQQLHQLQ QLQQQSQQQQ QSFEASCDPW GGECGGGGAG GSGGGGGASG 120
  121 GGGASGAGAQ QHQYQHPHPY PH

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 0.989
Match: 2iy3B
Description: No description for 2iy3B was found.

Predicted Domain #4
Region A:
Residues: [865-1090]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PHPYPHQTSV IQQQQSVTSY ESLKKSKSQG GSTTEHYSKQ QLTATTTTTT TTTIATKYNS  60
   61 KQYKQQQQQN NNLNSNQPNN QIAPLVMKKK NNSHIFFYQY TTHTHTNTHF KCNKLDGTFS 120
  121 RSRSSSMSSI DMSSSESVTC LAFIESYAKR NDILTLVPTL WIGTSFGSIL TLFITMPERD 180
  181 VRKSQPVLIT INGGPVVRLK GSITSMSFLD SYGSIIPYTF ETWRDE

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [1091-1168]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KRDNKDRTPT KSSSRTSPTF TPTTANTLSN TSVAGGASAG GGAGGGGGAG GGAASGGAAA  60
   61 GGPAGGGAGA GSAAGAAG

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #6
Region A:
Residues: [1169-1286]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GVGSGVTSGG GMSSSSASSS GISGSVSTGL ETLTDRQYIV IASEKQTKVF DVANQCCINR  60
   61 IQLSEMDFAV KAETITMKDG SCLATYLSNG HLMVHSLPSL KLLLDTDFLP LMELSFQT

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #7
Region A:
Residues: [1287-1403]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KCKQGIVDPM LSIWGQQIIV HEDTTQISKI FCFSHKGHGL YMASPTEIQK FTISSEFCQF  60
   61 ILEMMGELYT VHEMPEQPKE GFFKGLFGGG AKLLDREELF GEQSGKPNRS VARHIPG

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #8
Region A:
Residues: [1404-1470]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PNLEQLGQRA STAASEISRA HQLAMERGEK LNLLEERAER MANTAQDFSG TAHQLMLKYK  60
   61 DKKWYQL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 18.39794
Match: 1urqA
Description: Crystal structure of neuronal Q-SNAREs in complex with R-SNARE motif of Tomosyn
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle