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View Structure Prediction Details

Protein: gi|22831959, gi|...
Organism: Drosophila melanogaster
Length: 1029 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|22831959, gi|....

Description E-value Query
Range
Subject
Range
Trf4-1-PC, Trf4-... - This gene is referred to in FlyBase by the symbol Dmel\Trf4-1 (CG11265, FBgn0030049). It is a protei...
506.0 [0..1] [1029..1]

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Predicted Domain #1
Region A:
Residues: [1-247]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDPFVGWFQK EQEGPSLCTW LKIWETNAQE MGALLNQQLQ QATTINGSTS SSSSSSNSGN  60
   61 NNNNNNNNII NNTITNTTNN TGNNSSAKPY LSRPYSSLNR VLNFRADSLE ILQQQQQQQQ 120
  121 LNGTTQRNST NINTTSGGST SSSADSTTNR DNNSPANSSS TNGPGAGTGT STGAGGTGTN 180
  181 SPATTASSTA ATTTGPATSM SDTSNNPPQS TTTPASRTNS IYYNPSRKKR PENKAGGAHY 240
  241 YMNNHME

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [248-681]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIAKYKGEPW RKPDYPYGEG VIGLHEEIEH FYQYVLPTPC EHAIRNEVVK RIEAVVHSIW  60
   61 PQAVVEIFGS FRTGLFLPTS DIDLVVLGLW EKLPLRTLEF ELVSRGIAEA CTVRVLDKAS 120
  121 VPIIKLTDRE TQVKVDISFN MQSGVQSAEL IKKFKRDYPV LEKLVLVLKQ FLLLRDLNEV 180
  181 FTGGISSYSL ILMCISFLQM HPRGIYHDTA NLGVLLLEFF ELYGRRFNYM KIGISIKNGG 240
  241 RYMPKDELQR DMVDGHRPSL LCIEDPLTPG NDIGRSSYGV FQVQQAFKCA YRVLALAVSP 300
  301 LNLLGIDPRV NSILGRIIHI TDDVIDYREW IRENFEHLVV VDRISPLPTA APTAYATANG 360
  361 APKYVIMPSG AVVQQLYHHP VQVPTAHGHS HAHSHSHGHA HPGAHLCQPY VTGTTVSAVT 420
  421 TTTTMAVVTV GVSA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 86.0
Match: 1q78A
Description: Crystal structure of poly(A) polymerase in complex with 3'-dATP and magnesium chloride
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
catalytic activity 0.222270543382941 bayes_pls_golite062009
transferase activity 0.00393984128503999 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [682-772]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GGVQQQQQQQ NATAHTHSQQ QTQNQSQSRH RRGSTSSGDD SEDSKDGDVV ETTSSAQEVV  60
   61 DIALSTPNGL ANMSMPMPVH AVGMPASNSW S

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [773-913]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GNGNGNGNSS SSTGSSTMGA TAASMTRSNS SSKHTYITSS PPKQPEIAHI AAQEMDPELE  60
   61 DQQQQQQHQE TSGGNGFIRP GDVGTGSNRG GGDGSGGRNY NQRNNHNSSG YYHQQYYVPP 120
  121 PMQQQLSKSN SSSNYHQQHH H

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [914-1029]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SHSHGNHSHR QQHHHQQQHH HQQRPQHLRV GGGNRYQKSL GGSPIISAGN ASNSSSNCSN  60
   61 SSSSSGSNNS RLPPLRGTLV NSSSAISIIS ISSESSIASS SSSSSRSGQD QQRDER

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


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Created and Maintained by: Michael Riffle