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View Structure Prediction Details

Protein: Ir7c-PA, FBpp0301563
Organism: Drosophila melanogaster
Length: 625 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Ir7c-PA, FBpp0301563.

Description E-value Query
Range
Subject
Range
gi|987866, gi|45... - gi|987866|emb|CAA61678.1| AMPA receptor GluR4/D [Gallus gallus], gi|45382593|ref|NP_990545.1| glutam...
493.0 [0..2] [625..215]

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Predicted Domain #1
Region A:
Residues: [1-204]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLHSAVHNVS LVYALVWAID NYYGMATSTP LAVVQFPTSR ESRRLHNDLI DAALGRSSGT  60
   61 GRIQFLLEDD RVEMTETDTD PPPPSGLTGR PIAIWFLDSL RSYFRLEMYL NQLGSPYKRN 120
  121 GFFLVIYTGL EDQPMESLKI MFRRLLNMYV LNVNVFLQRD GTVHLYTYYP YGPHHCQSSL 180
  181 PVYYTAFQDL AAPANGFGLT KPLF

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [205-288]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PRKLTNMHGC EMVVATFEHR PYVIIEDDPK TPGGRSIHGI EGLIFRSLAE RMNFTIKLVE  60
   61 QKDKNRGEIL PDGNFTGILK MMVD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 24.69897
Match: 1yaeA
Description: Structure of the Kainate Receptor Subunit GluR6 Agonist Binding Domain Complexed with Domoic Acid
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [289-625]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GEVNLTFVCF MYSKARSDLM LPSTSYTSFP IVLVVPSGGS ISPMGRLTRP FRYIIWSCIL  60
   61 VSLIFGFVLI CLLKITALPG LRNLVLGRRN RLPFMGMWAS LLGGLALYNP QRNFARYILV 120
  121 MWLLQTLILR AAYTGQLYLL LQDVEMRSPI KSLSEVLAKD YEFRILPALR TIFKDSMPTT 180
  181 NFHAVLSLEE SLYRLRDEDD PGITVALLQP TVNQFDFRSG PNKRHLTVLP DPLMTAPLTF 240
  241 YMRPHSYFKR RIDRLIMAMM SSGIVARYRK MYMDRIKRVS KRRNLEPKPL SIWRLSGIFV 300
  301 CCAGLYLVAL IVFILEILTT NHRRLRRAFN VINRYAA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 20.045757
Match: 2a5sA
Description: Crystal Structure Of The NR2A Ligand Binding Core In Complex With Glutamate
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
catalytic activity 0.144254316055515 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle