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View Structure Prediction Details

Protein: FBpp0309623, FBp...
Organism: Drosophila melanogaster
Length: 961 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FBpp0309623, FBp....

Description E-value Query
Range
Subject
Range
gi|68388302 - gi|68388302|ref|XP_696268.1| PREDICTED: similar to slow myosin heavy chain 1 [Danio rerio]
288.0 [0..35] [955..1843]

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Predicted Domain #1
Region A:
Residues: [1-38]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPVFHTKTIE SILDPVAQQV SRLVILHEEA EDGNAMPD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 20.0
Match: 1u6hA
Description: Vinculin head (0-258) in complex with the talin vinculin binding site 2 (849-879)
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [39-961]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LSRPVQVVSA AVANLVKVGR DTINSSDDKI LRQDMPSALH RVEGASQLLE EASDMLRSDP  60
   61 YSGPARKKLI EGSRGILQGT SSLLLCFDES EVRKIIQECK RVLDYLAVAE VINTMEQLVQ 120
  121 FLKDLSPCLS KVHREVGARE KELTHQVHSE ILVRCLEQVK TLAPILICSM KVYIHIVEQQ 180
  181 GRGAEEAAEN RNYLAARMSD ELQEIIRVLQ LTTYDEDTSE LDNLTVLKKL SNAISNKMEQ 240
  241 ANEWLSNPYA LRGGVGEKAL RQVIDNATEI SERCLPQDSY PIRKLADEVT AMANTLCELR 300
  301 QEGKGQSPQA ESLVRGIRDR MGELKSLVHQ AVLGVDKAGV QQTAHTIQGR LEQAVKWLQH 360
  361 PEINDGGLGE RAINLIVEEG RKVAEGCPGH QKAEIQQLCD EVERLKRQAA GSGPAAKQAA 420
  421 KQLTQKLYEL KAAIQNALVN RIVQDFMDVS TPLKQFTEAV LQPEGTPGRE QNFNQKSNNL 480
  481 QAFSDRASKT SRMVAAGGAC GNKKIAEILL SSAAQVDSLT PQLISAGRIR MNYPGSKAAD 540
  541 EHLQNLKQQY ADTVLRMRTL CDQATDPADF IKTSEEHMQV YAKLCEDAIH ARQPQKMVDN 600
  601 TSNIARLINR VLLVAKQEAD NSEDPVFTER LNAAANRLER SLPAMVGDAK LVATNIADPA 660
  661 AAAAWKNSFQ RLLGDVREVR DAIAPPQPPP LPTSLPPPIP ELSALHLSNQ NAERAPPRPP 720
  721 LPREGLAPVR PPPPETDDED EGVFRTMPHA NQPILIAARG LHQEVRQWSS KDNEIIAAAK 780
  781 RMAILMARLS ELVLSDSRGS KRELIATAKK IAEASEDVTR LAKELARQCT DRRIRTNLLQ 840
  841 VCERIPTIGT QLKILSTVKA TMLGAQGSDE DREATEMLVG NAQNLMQSVK ETVRAAEGAS 900
  901 IKIRSDQTSN RLQWVRRQPW YQY

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 32.69897
Match: 1tr2A
Description: Crystal structure of human full-length vinculin (residues 1-1066)
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle