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View Structure Prediction Details

Protein: gi|24650714, gi|...
Organism: Drosophila melanogaster
Length: 1010 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|24650714, gi|....

Description E-value Query
Range
Subject
Range
gi|73987536 - gi|73987536|ref|XP_533958.2| PREDICTED: similar to transcription elongation factor B polypeptide 3 b...
487.0 [0..3] [1008..676]

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Predicted Domain #1
Region A:
Residues: [1-432]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLPSTGLFKG FLCPYFDGQD AASCKRPFCH FKHARKDELE AAPPAEPSPV PKYKPAPKLL  60
   61 SLPLPQITLC APRKKSNLEY HPEKPALDAS PAKKKQEASV DSAPKYVPGQ PSVTNGEEYD 120
  121 DWQAVLEKEI DEQMQVEIEE QVQNNDEEQK IDTVAENEED QENTQLTDAR DSHEKDRKPS 180
  181 KERERDIEKK KIRELKREKI KDRDRDRDRD REKDKEKSKE RDREKEKNDR DKRKSSHSDK 240
  241 ERSKERNTSS SSSSKHKSSS SSSSSKKSSS SDKHRDDKSS SSRHKSSSSS SSSKSHHHKS 300
  301 SSSSSRSKTK RSSSSSKSAG TSKSEPEADK DTEAAVLTPA EPMDDLDDMD FDFEADTSEG 360
  361 EIVRQCEMIF DEMEKKFAQM HKDEGGNANP ESSRKRKAPS PDIDTFTEAA TAALQKRRVA 420
  421 HENADKITPH LA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 19.69897
Match: 1i84S
Description: Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [433-519]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PSAAMRKPNH VRNAMQAIFN RRAELRRQEK LQAEASAEQV RQAQERVRQA QEELRQAKVN  60
   61 SNLTPLISRS ALTPPVRSAR SIAPVAN

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [520-807]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IVAIARAKKK IEELQAEKKP AFTPAQSFKG AGRVAHKPTA ALDKAAPVSN AEKPTVLDPS  60
   61 SSKISYNVRI QYYEMMVRHC TVIYPQLADA WERAQVEELT VFKKCNTPAI YKNSCMLAIN 120
  121 KLRKEALEAG NKPSVACKTV SHEMMLGGKR ALTTSWSVEK KGKLSSLGNG EPFDALDAEK 180
  181 AYKMVFDLRL TEEQLVENGY PRPGDKRGSA VIRACRPNRR PNQKERYCSR CGKVFSLDIY 240
  241 EHQSFDMCNY HPKSTGYRRG FTDHQHRCCQ QPAGTPGCTY ANYHVSDY

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.03
Match: 1pqvS
Description: RNA polymerase II-TFIIS complex
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [808-1010]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YDPEKLTCFV KTIERGEEFV PTKKDIYALD CEMCYTTHGI ELTRVTVVDI NGRSVYDALV  60
   61 KPDNQIVDYN TTWVNVAFRL FRINLQYSDF SYSGITEAML SNETRTIRDV QAVLMSMFHA 120
  121 KTVLVGHSLE SDLKALKLIH DVVVDTSVLF PHKMGPPKKR ALKTLCIENL KRIIQESEAG 180
  181 HDSAEDAEVC IQLIKYYLRN KIS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 44.39794
Match: 1wljA
Description: human ISG20
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
catalytic activity 0.485910322334531 bayes_pls_golite062009
nuclease activity 0.318985867549147 bayes_pls_golite062009
hydrolase activity 0.278122673215692 bayes_pls_golite062009
hydrolase activity, acting on ester bonds 0.251364069223802 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle