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View Structure Prediction Details

Protein: CG5053-PA
Organism: Drosophila melanogaster
Length: 607 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CG5053-PA.

Description E-value Query
Range
Subject
Range
gi|68388302 - gi|68388302|ref|XP_696268.1| PREDICTED: similar to slow myosin heavy chain 1 [Danio rerio]
250.0 [0..49] [601..2136]

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Predicted Domain #1
Region A:
Residues: [1-83]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MELKVWVEGI QRIVCGVTVN TTCQDVVFAL AHATGKVGRF TLIERWRNNE RHLAPNENPM  60
   61 KLLLKWGEYA NDVQFILQRS ENK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 34.154902
Match: 2cs4A
Description: Solution structure of N-terminal domain of chromosome 12 open reading frame 2
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [84-255]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TQQQQQQQQQ QQQNNNNNNN YAVMTTTKKP LGPNNNNNNK PAPTLLKQKS NVELSYRTKE  60
   61 LKKSFGGHDA KQFDNIGIVK GIPQQQQLQS QQTAMGAPAS PPQEQLTPQD NNNVAPLVPK 120
  121 HEKSLSNPLD MTSTGSNPPA PTNGYNDFYN NNSSSNQHIY SQLSKSSNEL RR

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [256-607]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SSPNEMYYNN NNNIVNNNNN SPELYKQTPT ISANGALVPP PYRDPPPPRN SPMCQGQRLA  60
   61 SSNADTMSNA SSSTNPFLSD YDQHSSHNTN SINNNSQAME EGEPMFQTTQ YNDLLQLIKF 120
  121 QREKITAQQM ELQKFDTEIV YLESKERDHA HELDAISREI SKADQIFRQG SEQLQTLQYV 180
  181 EEENELVKQQ EKTLKSEIAL LRSKLANCET ELLQCKNKMR LLMDDIELEQ QHQQQTNRQT 240
  241 VERDFLMEME RIQSEIDQAL HNTDTSNKTA DSLKKELLMI EHAIADKKRQ VEQLVNEMKE 300
  301 VNLQSLTVTT TEEIKHLLEG PNKQGSSRRI IGSPRQLETA VPTSKNPHGV WV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 15.522879
Match: 1i84S
Description: Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

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Created and Maintained by: Michael Riffle