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View Structure Prediction Details

Protein: mbc-PA
Organism: Drosophila melanogaster
Length: 1970 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for mbc-PA.

Description E-value Query
Range
Subject
Range
DOCK1_MOUSE - Dedicator of cytokinesis protein 1 OS=Mus musculus GN=Dock1 PE=1 SV=3
1897.0 [0..1] [1886..1]

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Predicted Domain #1
Region A:
Residues: [1-133]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSVWSDCNAK QAEFGIAKCN FDQESKPHRL NLDVGDAVII LKETTHWYYG YRQKAKEIRG  60
   61 IFPKSYIHLC EYNIVNGEYC IQRTDIVEEI TKVLLEWGSI AKDYFLTTNP SFPKIRRKMN 120
  121 ELNNNRAALI SGN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 5.69897
Match: 2dl3A
Description: No description for 2dl3A was found.

Predicted Domain #2
Region A:
Residues: [134-322]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LPLDEVRKVK LLATNQIDTG NKLLGLDMVV RDESGDILDT NAICTTELYE QHMHAVQRID  60
   61 KANRLSSERG TTRTPNKYSH NILLHVNAFV CKFQEDSDLL FTLFDGETHK PISENYVVKW 120
  121 SRTGIARDTD QIDNNRVLFT DLSKSDLAIA KMYLVCYAIR IGSMEFKDSA ESKRTSMSIA 180
  181 NSMLNASSR

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [323-440]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KASQLSVSSS GSSSSNGEYI IRRPFGVACK DLTPFINKSD DFRGNIDLPF IMCEKETLDG  60
   61 TLRKLIANKD IGKIDSKMAV TIEVLRGDIK QIKEEFPRLM HTNVPVARKM GFPEVILP

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [441-580]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GDVRNDLYLT ICSGEFARIA KTSEKNVEVS VCVANEQGYL MPGVLSIGAG HQPIDEYKSV  60
   61 VYYHDDKPKW QETFKIHVPI EDFKQCHLRF VLKHRSSNEQ KDRTEKPFGL AYVRLMQANG 120
  121 TTITQGQHIL AVYKIDHKKY 

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.04
Match: 2dmgA
Description: No description for 2dmgA was found.

Predicted Domain #5
Region A:
Residues: [581-641]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DKTVANCYLE LPATVAELQG AKPSIGGLTL LPKDQLSIGV NLCSTKLTQS VSLLGLLNWS  60
   61 A

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #6
Region A:
Residues: [642-1009]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HKETLEQSLN ALSTVPGEEV VKFLQDILDA LFNILVENDH PEKYDQLVFM SIIHLIETVS  60
   61 DLKYQHFLSV LDVYINESFS FTLAYTKLMD VLQKNISEAI SPKEKSADGN DLEESPEVRR 120
  121 LYKTTRYLHY VMKFVIRSRV LYAEMNCNTD YMDFATRLQE LLRMFIDMIG CPSNLLKSEG 180
  181 ALLKNLHIIA TDLMQVFEHV RLSISIVEIL EKFPPRRLTQ SKMGCIKDFV ETKLFTLPKC 240
  241 RAILLPVFCK HIKDHLESKE EIAECINIMN NILKLLFRSD VGSTHNDIRD IMIILFRTVM 300
  301 KAAHALDRDT GLVGKFFAIM LGILQRMDAQ HYEYFVKDLH QSGELKHFVI EILLVFEELV 360
  361 SPHQKAVF

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 3.30103
Match: 1wa5C
Description: Crystal structure of the exportin Cse1p complexed with its cargo ( Kap60p) and RanGTP
Matching Structure (courtesy of the PDB):

Predicted Domain #7
Region A:
Residues: [1010-1143]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PRDWMDMIMH QNTVILGALK HLTVVITDYF LCPFEKQIWS NFFQCSIAFL VQSPLQLNDF  60
   61 NDNKRQIVFA RYRDIRKDTA MEIRKMWFQL GQHKPKFVPQ LVEPILEMSM IPEKELRQET 120
  121 IPIFFDMMQC EYYS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #8
Region A:
Residues: [1144-1351]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SRLEHESYGD TKFNNAHHKG NFSDFKTAMI EKLDILIGAG KGDAEYKHLF ETIMLERCAA  60
   61 HNTLNVDGTA FVQMVTRLMD KLLEYRFIIQ DESKENRMAC TFSLLQFYSE VDLKEMYIRY 120
  121 VNKLCALHME FENYTEAAFT LKLHTELLRW TDTELSHQLR SYRHNNCRTH RQLKEALYFE 180
  181 IMEYFDKGKQ WECAIDMCRV LARQYEEE

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #9
Region A:
Residues: [1352-1497]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IFDYLKLAEL LNRMALFYEK IIKELRHNSE YFRVCFYGRG FPRFLQNRVY IFRGKEYERH  60
   61 SDFCARMLVQ HPQAELMQTL EAPGDDITNS DGQYIQVNKV EPIMGQAFNK FNDKIINNEI 120
  121 VKYFTANNVQ KFQFSRPFRD STNGGD

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #10
Region A:
Residues: [1498-1652]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RDDVRNLWLE RTELRISYPL PGILRWFPVV ETNTFKISPL ERAVEIMKDT NRDIRQLVIL  60
   61 HKSDETLHIN PLSMKLNGIV DPAVMGGFAK YEEAFLTDDY LEQNPDDKEL VEELKELIAN 120
  121 QIPLLDLAIQ LHRLRAPDSL KALQEHLERC FADMQ

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #11
Region A:
Residues: [1653-1970]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QHVEQRYGRK SCDLKIERDS VVMRRPNSFL PSLFDGSNNR HSETSMGSSD SGLSKSTFLP  60
   61 RPQTNSIKNP FSGLSFNTRP SLGHSPSIKS NKSKDKTPSK RRTKDGKVKE REAHSLSSSQ 120
  121 WYTPPLSTIT STPEKEINTS IASLASTSNS SLSGPKTPDP HVLTEELTPK RPLRSEMEKE 180
  181 RRLSRPASIA TPTASIKNFP DTRSLSESSN RNSVETTDST SEEDIRPPPL PAKARDSTDF 240
  241 TSLSQNMDWT PNGYAMLSTI SNTSSMSTTS TLTKTSITNT TYEYLETTNF SLVGAIDGNK 300
  301 PRPPTPPPKP SRHSKHIP

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.58
Match: 1h1kI
Description: THE BLUETONGUE VIRUS (BTV) CORE BINDS DSRNA
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle