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View Structure Prediction Details

Protein: HP1c-PA
Organism: Drosophila melanogaster
Length: 237 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for HP1c-PA.

Description E-value Query
Range
Subject
Range
gi|63146377 - gi|63146377|gb|AAY34034.1| heterochromatin protein 1C [Drosophila simulans]
246.0 [0..1] [237..1]
gi|109508460 - gi|109508460|ref|XP_001062696.1| PREDICTED: similar to chromodomain helicase DNA binding protein 9 i...
192.0 [0..4] [184..768]
gi|82918135, gi|... - gi|82918135|ref|XP_906533.1| PREDICTED: chromodomain helicase DNA binding protein 9 isoform 6 [Mus m...
190.0 [0..4] [184..768]
gi|87130801 - gi|87130801|gb|ABD24032.1| PRIC320 isoform 1 [Homo sapiens]
190.0 [0..4] [184..769]
gi|114662479 - gi|114662479|ref|XP_001165654.1| PREDICTED: chromodomain helicase DNA binding protein 9 isoform 2 [P...
189.0 [0..4] [184..769]

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Predicted Domain #1
Region A:
Residues: [1-174]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVKNEPNFVV ERIMDKRITS EGKVEYYIKW RGYTSADNTW EPEENCDCPN LIQKFEESRA  60
   61 KSKKRGEKKP KCEEIQKLRG YERGLELAEI VGATDVTGDI KYLVRWQFCD EFDLVPSAQI 120
  121 VEKDPQMLID YFQKMAPYSR HIAMRMKGVP EELRLAASRT SYPHISSAPV EVPP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 15.30103
Match: 2b2uA
Description: Tandem chromodomains of human CHD1 complexed with Histone H3 Tail containing trimethyllysine 4 and dimethylarginine 2
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [175-237]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EVDQSAELAG HLGGIAPQVD QAPQHHAPMD LANDTDDLAS VSYSIPVPGV GDIAIDVPMA  60
   61 ENQ

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle