YRC Public Data Repository - Protein Structure Prediction

Protein:	CG5377-PA
Organism:	Drosophila melanogaster
Length:	278 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CG5377-PA.

Description	E-value	Query Range	Subject Range
gi\|21430884 - gi\|21430884\|gb\|AAM51120.1\| SD22712p [Drosophila melanogaster]	175.0	[0..1]	[278..1]
gi\|74003990 - gi\|74003990\|ref\|XP_535867.2\| PREDICTED: similar to Valacyclovir hydrolase precursor (VACVase) (Biphe...	162.0	[0..2]	[275..34]
gi\|214034777, gi... - gi\|254479271\|ref\|ZP_05092613.1\| hydrolase, alpha/beta fold family, putative [Carboxydibrachium pacif... gi\|20515541, gi\|... - gi\|20807053\|ref\|NP_622224.1\| alpha/beta superfamily hydrolase/acyltransferase [Thermoanaerobacter te... gi\|20807053 - gi\|20807053\|ref\|NP_622224.1\| predicted hydrolase or acyltransferase (alpha/beta hydrolase superfamil...	161.0	[0..26]	[276..4]
gi\|47564986, gi\|... - gi\|47564986\|ref\|ZP_00236030.1\| lipase, putative [Bacillus cereus G9241], gi\|47558359\|gb\|EAL16683.1\| ...	160.0	[0..12]	[277..35]
gi\|83633852, gi\|... - gi\|83645809\|ref\|YP_434244.1\| alpha/beta superfamily hydrolase/acyltransferase [Hahella chejuensis KC...	159.0	[0..26]	[276..47]
gi\|88707370, gi\|... - gi\|88714312\|ref\|ZP_01108386.1\| hydrolase, alpha/beta hydrolase fold family protein [Flavobacteriales...	158.0	[0..15]	[278..69]
gi\|55242608, gi\|... - gi\|58382165\|ref\|XP_311731.2\| ENSANGP00000013613 [Anopheles gambiae str. PEST], gi\|55242608\|gb\|EAA074...	158.0	[0..6]	[274..6]
gi\|15966231 - gi\|15966231\|ref\|NP_386584.1\| putative haloperoxidase protein [Sinorhizobium meliloti 1021] gi\|15075501 - gi\|15075501\|emb\|CAC47057.1\| Non-heme chloroperoxidase F (Chloride peroxidase, CPO-F) [Sinorhizobium ...	157.0	[0..11]	[273..47]

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Predicted Domain #1

Region A:
Residues: [1-278]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLGNLCRLVG ARSPITRRLL HTERKVRVNG SDLNIVESGS GERSLLLMPG ALGSSWTDFR  60
   61 PQIEQLPKLL PGHTIIAWDP PGYGKSVPPQ RKFGLEFFRE DAQAAVDLMR ALDRPRFSIL 120
  121 GWSDGGITAL IVAGRHAEAV DRLAIWGAGA YLNADEVKAL KNIRDVAKWS PRMREPMEKV 180
  181 YGVERFPQLW AEWVDAACAF YDQRDGDFCR TEVEKIKIPT FILHGKKDPM IAAEHIPWLR 240
  241 ERLPHAEYYE FPEGKHNIHL RYAEEFNKLV ADFFNKNN

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	37.39794
Match:	1va4A
Description:	Pseudomonas fluorescens aryl esterase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	1.39629727416851	bayes_pls_golite062009
hydrolase activity	0.889604807785227	bayes_pls_golite062009
hydrolase activity, acting on ester bonds	0.264183693934251	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: