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View Structure Prediction Details

Protein: Prp18-PA
Organism: Drosophila melanogaster
Length: 340 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Prp18-PA.

Description E-value Query
Range
Subject
Range
gi|47216030 - gi|47216030|emb|CAG11361.1| unnamed protein product [Tetraodon nigroviridis]
391.0 [0..1] [328..1]

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Predicted Domain #1
Region A:
Residues: [1-169]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDILKAEIAR KRKLLEQRQL VDEKKKYFRR GDLNAKNTEE VLQKVGYIKQ ESVEAQGQTT  60
   61 EGAYSFVADG QNILPRTEVI RRLRERGEPI LIFGETEPEA FDRLRQCEIS QPEANRGFRN 120
  121 DFQEAMEQVD AAYLQEMFAN TPTTKEDKKS DFAELDESVS WESIQTMAA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 3.045757
Match: 2i1jA
Description: No description for 2i1jA was found.

Predicted Domain #2
Region A:
Residues: [170-340]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NMGRNKDYDM DVIITLLTFL LKLWNDQIAN YSKHEKMSTK VKMTRVIYTQ TKEYVKPLFR  60
   61 KLKHHTLPED ILDSLRDICK HLLNRNYITA SDAYLEMAIG NAPWPIGVTM VGIHARTGRE 120
  121 KIFSKNVAHV MNDETQRKYI QGLKRLMTKC QEYFPTDPSK CVEYVSKKDR E

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 45.39794
Match: 1dvkA
Description: Functional domain of the splicing factor Prp18
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
8.4933513491836 bayes_pls_golite062009
second spliceosomal transesterification activity 5.51692977589724 bayes_pls_golite062009
catalytic activity 0.60409960326459 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle