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View Structure Prediction Details

Protein: CG16941-PA
Organism: Drosophila melanogaster
Length: 784 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CG16941-PA.

Description E-value Query
Range
Subject
Range
gi|55244637, gi|... - gi|58376969|ref|XP_309321.2| ENSANGP00000008201 [Anopheles gambiae str. PEST], gi|55244637|gb|EAA051...
520.0 [0..22] [784..1]

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Predicted Domain #1
Region A:
Residues: [1-122]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MATLDAEANE EQFGNDQPKS MSGPIIGIIY PPPEVRNIVD KTASFVARNG PEFEARIRQN  60
   61 ELGNPKFNFL NGGDPYHAYY RHKVNEFREG NDAGITALAS MKQLAVTSAA QQRQQELLKQ 120
  121 VV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 23.0
Match: 2dt6A
Description: No description for 2dt6A was found.

Predicted Domain #2
Region A:
Residues: [123-276]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EQQFVPKEPP PEFEFIADPP SISALDLDIV KLTAQFVARN GRQFLTNLMS REQRNFQFDF  60
   61 LRPQHSLFQY FTKLLEQYTK VLIPPKDLLG KLRSESAPGR SSMNQVLEQV KYRANWQRHQ 120
  121 EAQRRREEEK IERERVAYAQ IDWHDFVVVE TVDY

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 26.154902
Match: 2dt7B
Description: No description for 2dt7B was found.

Predicted Domain #3
Region A:
Residues: [277-489]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QPFESGNFPP PTNPDEVGAR VLMEERLMDE EGDTEMQIES DDEGDSQANN LLDSGLKLSQ  60
   61 MENRVGIQMK NVSSYGQPTG PKRDNTQVQD MDEASSDEDT PTTKLQPSVA PMLPPTHDKV 120
  121 VVKKYDPKAT QPKQAPMPTD EYLISPITGE KIPASKVSEH MRIGLLDPRW VEQRDKHTVE 180
  181 KINQDNVFAA GTAIEASLKQ LAERRTDIFG VGD

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [490-678]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EETVIGKKLG EEETKKDDRV TWDGHTSSVE AATRAARANI TLEEQIHQIH KVKGLLPDEE  60
   61 KEKIGPKPVG NKATLSAPPQ PSTKSQHSHS SQSQHHQGGG GGHHGHHNPH HHHPPHQQAP 120
  121 PHQSHHHHPP QQPQPVMQLM QLRPTMMQPP FGAGGGGYMN MQPGGIPQQI APAPPVDIME 180
  181 EEPPSKKIR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 6.69897
Match: 1m2vB
Description: Sec24
Matching Structure (courtesy of the PDB):

Predicted Domain #5
Region A:
Residues: [679-784]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SEDNLIPEAD FIATHKSPVT IQVLVPNSDK SEWKLNGQMI AVTMALSEPI ANLKTKLQDE  60
   61 TGMPPAKQKI FYEGMFFKDS NTMAFYNLVN GTTVHLQVKE RGGRKK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 18.522879
Match: 1we7A
Description: Solution structure of Ubiquitin-like domain in SF3a120
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 2.786655943372 bayes_pls_golite062009
RNA binding 2.5865157751042 bayes_pls_golite062009
nucleic acid binding 1.9984951714209 bayes_pls_golite062009
structural constituent of ribosome 1.967509006593 bayes_pls_golite062009
transcription regulator activity 1.96195140258726 bayes_pls_golite062009
protein binding 1.86841453215444 bayes_pls_golite062009
DNA binding 1.68336605464756 bayes_pls_golite062009
structural molecule activity 1.52853261170163 bayes_pls_golite062009
tubulin binding 1.52077315590062 bayes_pls_golite062009
cytoskeletal protein binding 1.27084865380092 bayes_pls_golite062009
microtubule binding 1.2489441153237 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle