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View Structure Prediction Details

Protein: Men-PB
Organism: Drosophila melanogaster
Length: 763 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Men-PB.

Description E-value Query
Range
Subject
Range
gi|7248646 - gi|7248646|gb|AAF43601.1|AF187998_1 malic enzyme [Drosophila melanogaster]
1128.0 [0..1] [763..1]

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Predicted Domain #1
Region A:
Residues: [1-205]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGNSSSICAD RNVITNFDEN GTPVYPTANN SQSPSSYSRG KERELGCYTK RNSNSNNNNS  60
   61 HERESQSCCS SRVCKNHTTT TTTTLEYELS NFAKLTTRIT TQSAAEVDTS PHTDTETHRD 120
  121 RDSNPGNIAL ATDLELPKGL PLSLSSRHHW NQLQSSLHAL HHQQQQQQQQ LRSYSSTSET 180
  181 NLEDKMSKPD SKLDKYAQRD RLGLW

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [206-763]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GTGDNEVVGS LSGFTRLLDK RYSKGLAFTH EERQQLGIHG MLPYVVREPS EQVEHCRALL  60
   61 ARLDQDLDKY MYLISLSERN ERLFYNVLSS DIAYMMPLVY TPTVGLACQR YSLIHQNAKG 120
  121 MFISIKDKGH IYDVLKNWPE TDVRAIVVTD GERILGLGDL GANGMGIPVG KLSLYTALAG 180
  181 IKPSQCLPIT LDVGTNTESI LEDPLYIGLR ERRATGDLYD EFIDEFMHAC VRRFGQNCLI 240
  241 QFEDFANANA FRLLSKYRDS FCTFNDDIQG TASVAVAGLL ASLKIKKTQL KDNTLLFLGA 300
  301 GEAALGIANL CLMAMKVEGL TEEEAKARIW MVDSRGVITR DRPKGGLTEH KLHFAQLHEP 360
  361 IDTLAEAVRK VRPNVLIGAA AQGGAFNQEI LELMADINET PIIFALSNPT SKAECTAEEA 420
  421 YTYTKGRCIF ASGSPFAPVT YNNKKFYPGQ GNNSYIFPGV ALGVLCAGML NIPEQVFLVA 480
  481 AERLAELVSK DDLAKGSLYP PLSSIVSCSM AIAERIVEYA YKNGLATVRP EPVNKLAFIK 540
  541 AQMYDLDYPR SVPATYKM

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 1000.0
Match: 2aw5A
Description: Crystal structure of a human malic enzyme
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle