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View Structure Prediction Details

Protein: Fmr1-PA
Organism: Drosophila melanogaster
Length: 684 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Fmr1-PA.

Description E-value Query
Range
Subject
Range
gi|74008639 - gi|74008639|ref|XP_866784.1| PREDICTED: similar to fragile X mental retardation syndrome 1 homolog i...
754.0 [0..1] [573..1]

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Predicted Domain #1
Region A:
Residues: [1-146]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEDLLVEVRL DNGAYYKGQV TAVADDGIFV DVDGVPESMK YPFVNVRLPP EETVEVAAPI  60
   61 FEEGMEVEVF TRTNDRETCG WWVGIIKMRK AEIYAVAYIG FETSYTEICE LGRLRAKNSN 120
  121 PPITAKTFYQ FTLPVPEELR EEAQKD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 76.30103
Match: 2bkdN
Description: Structure of the N-terminal domain of Fragile X Mental Retardation Protein
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [147-312]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GIHKEFQRTI DAGVCNYSRD LDALIVISKF EHTQKRASML KDMHFRNLSQ KVMLLKRTEE  60
   61 AARQLETTKL MSRGNYVEEF RVRDDLMGLA IGSHGSNIQA ARTVDGVTNI ELEEKSCTFK 120
  121 ISGETEESVQ RARAMLEYAE EFFQVPRELV GKVIGKNGRI IQEIVD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 30.0
Match: 2cpqA
Description: Solution structure of the N-terminal KH domain of human FXR1
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [313-684]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KSGVFRIKVS AIAGDDEQDQ NIPRELAHVP FVFIGTVESI ANAKVLLEYH LSHLKEVEQL  60
   61 RQEKMEIDQQ LRAIQESSMG STQSFPVTRR SERGYSSDIE SVRSMRGGGG GQRGRVRGRG 120
  121 GGGPGGGNGL NQRYHNNRRD EDDYNSRGDH QRDQQRGYND RGGGDNTGSY RGGGGGAGGP 180
  181 GNNRRGGINR RPPRNDQQNG RDYQHHNHTT EEVRETREMS SVERADSNSS YEGSSRRRRR 240
  241 QKNNNGPSNT NGAVANNNNK PQSAQQPQQQ QPPAPGNKAA LNAGDASKQN SGNANAAGGA 300
  301 SKPKDASRNG DKQQAGTQQQ QPSQVQQQQA AQQQQPKPRR NKNRSNNHTD QPSGQQQLAE 360
  361 NVKKEGLVNG TS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 32.69897
Match: 1y0fA
Description: No description for 1y0fA was found.

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