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View Structure Prediction Details

Protein: sec8-PA
Organism: Drosophila melanogaster
Length: 985 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for sec8-PA.

Description E-value Query
Range
Subject
Range
gi|21429190 - gi|21429190|gb|AAM50314.1| SD04949p [Drosophila melanogaster]
698.0 [0..1] [985..1]

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Predicted Domain #1
Region A:
Residues: [1-435]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDAPPPTKPP RGVKYGKDES AGCGFLVNVI KSLGFSETTE ERQKEKQKIE AEFKRSDLRL  60
   61 NELVSRHDQQ LTQVLPLFSQ VSSEVTASRE RIHAVKENLG VCKRLLQCRR DELRKMWMDA 120
  121 VQHKYVLEML EQIQELRKVP QRVVGYTAKR QYLHASKALT DALTTLNGPL QAVEGLSDLR 180
  181 TDLQTRRQQL YQRLHEELVT QVYTNSANEA LSSFQRTNSS RLNSSFTRGI GARRSTDRIE 240
  241 ANARVRKALA EMAQSFDLDK AEVIEDADLI YPELSMSYFV AIIVESFGML HKVPDSLETL 300
  301 RVQIQTELLN VVRHTTHQLS VSGATADTNP LLSLLEVIFK QFKAIAKTHS LLLKNYLSVG 360
  361 QKYSVVGPQP YDLTDFWAQA QSVLQLLLTD YLDIQNAAAD ESAQTGFSEP TSNINSYFLR 420
  421 RKVPSTKRSM FKFDK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 18.154902
Match: 1i84S
Description: Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [436-487]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SSHVGTSNNS DAFKEHRRNA SDASVDDNLA GQLGGSGKGS TSGLFPHEKK QR

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [488-985]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EKILICTPDQ SIITKVYLPL MGYIKEIENF MKCKPGQPCS LHDFLDNYIK DTFLTKGHNR  60
   61 NLQLTIESLS KNQDAWRTII SPEEIKALNL SRPLLQSTVM VERRLMETKN LIQDLPCYSE 120
  121 DLLKMVCALL KAYREICQAA YRGIVQPDSE DKRIYSVAWL KDEDISRFLK TLPNWTDLKT 180
  181 YSQKSRHNRK LHRGSFEPSE EESPLQVQQR NIREAEMLTS NLGEGGITQQ EILVEISVLK 240
  241 ELAILQESME WFSCRVSEFA NDLRRPLVNG LNAVPAECGA DIAVKDGTIK VMTNLALEFD 300
  301 ELANTCLLVL HLEVRVQCFH YLRSKSSVRT NSYVGSKDDI LEPDRQVQVL TKRLSEMDEA 360
  361 FSATLHPRKT RYIFEGLAHL ASRILIQASN YLEHIDQITV QRMCRNAIAL QQTLSNITAS 420
  421 REVALDQARH FYELLCMEPD EILNALLERG TQFSEMQLLN ALQLSCKSFG ITDANLLASY 480
  481 QQKLSDILGA KPSKGVVV

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 0.995
Match: 2a2fX
Description: Crystal Structure of Sec15 C-terminal domain
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle