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View Structure Prediction Details

Protein: tacc-PC
Organism: Drosophila melanogaster
Length: 1308 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for tacc-PC.

Description E-value Query
Range
Subject
Range
MYH1_PIG - Myosin-1 OS=Sus scrofa GN=MYH1 PE=2 SV=1
389.0 [0..305] [1307..839]

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Predicted Domain #1
Region A:
Residues: [1-349]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDFLANIIKR PKSIATTGIS TNQPTTMEAL EAASPADECS TPRDKGGVTL VSAHLDSLLE  60
   61 SASEELQRLE GKHCELFMES ISNPLPAPED STDSREEIQK FLSEINFNLN QVSANEMEHL 120
  121 QAMSGELSPL AVKPSPKPTS MDQQKAMAAA LGHQTAVPGG LKPEDDLVPK FGGLPEFDET 180
  181 QIPELAPLST DMDTQLKSNH SDSDVFVECL SLHSERYTGD RSELEAYSSA LNDVLEQQLS 240
  241 MTSVSTLGAE FNDPLAVSQH NNVSYEAMDV DDLNETMEML KDVLNAEDRH LMQTHILSVT 300
  301 QSKPENNFVH YHPNQEQNRV ELDQLAKHSK PNSDAKESES LVESVLSEE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 16.221849
Match: 1i84S
Description: Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [350-501]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SGTQSFEPKL TLSALDSTKD LAKHQEEMQT NTKDIFQKEK HHPVSSAQVK DAQNPKEPEK  60
   61 ALNLKEASSE LSTKSAKSLE YPNQEKQFSV AVESMERPCT AISLEQNASP AMEATEDRTV 120
  121 EELDQMDVDE SMKVDDATVL NSCRQEQINA HS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 6.0
Match: 2fxmA
Description: No description for 2fxmA was found.

Predicted Domain #3
Region A:
Residues: [502-628]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PVSSKFFLKL CVQNDTDCQD NKMDQKTAGK ESALKMTEIE LPVESVPSAS LSPPTPALQA  60
   61 KIIELSLSPP IPTHRPKTAE ELEFLALREL PLPDGVSTAG KVECKQLSHG LVPIVAVLPT 120
  121 PLYLDLK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [629-695]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GNTTTASLPE PTSPSFPIKE PAEKQSHFPR SPRAQLEQKD MPYLEEAVVE RSSHRKQSDF  60
   61 GVIAKSP

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [696-939]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IVFELTQPSP EKQHLNETLP MSEISPTSSN MTFDSGSITE DKSQKGTENI EPSSTLAVSL  60
   61 GSVDDKQRRT FSVVQPTKEE EEAKSRRTFC MENENPRRTF CMQQNASPAV EATEDTGADE 120
  121 VMDVDISMRA DEVAVMKSHQ QTWKERQAPI SNSPPIPTHQ RLNRPPEAIS PVSPLGNGTV 180
  181 VLEEQTLSAK EQATLSASDE KDDVFLEHFG AISPVSDDMF KTSSASNNQA KFRVNADEET 240
  241 GGKG

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #6
Region A:
Residues: [940-1036]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ASAMIRKRSG TAGEQEEIFD AEFHDGVNNQ NRSNSVPIDR SSLLLKFDPL LGAPVPVNHP  60
   61 NQQEQALQNI LGSNQHQNRL LSPTLEEHET SDGNQSF

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #7
Region A:
Residues: [1037-1308]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GVISSAKDTA KKWDFKPPVD RTKKHVKMSV DVIDNDCNKT FDNSNTNTED KTHNYNDMDE  60
   61 LEKKIKNEVT RSEDIEKKLK EGELREEALI KRITEKDKTN AKLNGVIEAY EKAIAELISE 120
  121 KEQQAQLHER QLQEVQADRD ANYHHLTSLE TTFSDLHVKY EKSKEMTSQL KSNEESLLAE 180
  181 RKQMMDNLRL QEQRYDKMKN HAMQQLEIAN KKLDTYSREH ADETKKLKAL LKKEEISRVS 240
  241 MTEQLQQKSR ENADLLKICE ELIYGKGQGG SS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 7.0
Match: 1c1gA
Description: Tropomyosin
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle