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View Structure Prediction Details

Protein: CG6485-PA
Organism: Drosophila melanogaster
Length: 238 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CG6485-PA.

Description E-value Query
Range		 Subject
Range
gi|109121568 - gi|109121568|ref|XP_001099724.1| PREDICTED: similar to NADH dehydrogenase (ubiquinone) flavoprotein ...
 348.0 [0..3] [228..20]
gi|73962198 - gi|73962198|ref|XP_537328.2| PREDICTED: similar to NADH dehydrogenase (ubiquinone) flavoprotein 2, 2...
 347.0 [0..3] [227..20]
NDUV2_PONPY - NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial OS=Pongo pygmaeus GN=NDUFV2 PE=2 SV=1
gi|111661782 - gi|111661782|gb|ABH12155.1| mitochondrial complex I subunit NDUFV2 [Gorilla gorilla]
NDUV2_PONAB - NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial OS=Pongo abelii GN=NDUFV2 PE=2 SV=1
NDUV2_GORGO - NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial OS=Gorilla gorilla gorilla GN=NDUFV2 P...
 346.0 [0..3] [228..20]
gi|119622017, gi... - pir||A30113 NADH2 dehydrogenase (ubiquinone) (EC 1.6.5.3) 24K chain precursor - human, gi|48735289|...
 346.0 [0..3] [228..20]
NDUV2_PANTR - NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial OS=Pan troglodytes GN=NDUFV2 PE=2 SV=1
 345.0 [0..3] [228..20]
NDUV2_BOVIN - NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial OS=Bos taurus GN=NDUFV2 PE=1 SV=3
 344.0 [0..3] [228..20]
NDUV2_MOUSE - NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial OS=Mus musculus GN=Ndufv2 PE=1 SV=2
 342.0 [0..3] [228..19]

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Predicted Domain #1
Region A:
Residues: [1-238] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLRLLQPIRR IHLAPVLRLG APVNATEIRK ALKFEFSKDN QRRVKALLAW YPQAEWKGAL  60
   61 LPLLDIAQRQ QGWLSISAVQ AVAETIKIDP MEAFEAAQFY TMFFMKPRGK YVVSVCTSTP 120
  121 CKLRGGDEIF EACKKTLNLE HGQTTPDMQF TLKEDYCMGA CVNAPVLAVN DDMYEDLDEK 180
  181 SLANILADLR NDKLPPAGPR NGRFASEPKG GLTTLKIQPP PPGFMMQKLP DPKTKKCQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 49.0
Match: 2fug2
Description: Crystal structure of the hydrophilic domain of respiratory complex I from Thermus thermophilus
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
NADH dehydrogenase activity 9.90105969982332 bayes_pls_golite062009
NADH dehydrogenase (ubiquinone) activity 8.92078442660684 bayes_pls_golite062009
oxidoreductase activity, acting on NADH or NADPH 8.81403581008074 bayes_pls_golite062009
NADH dehydrogenase (quinone) activity 8.78237088091479 bayes_pls_golite062009
oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor 8.15019987387908 bayes_pls_golite062009
oxidoreductase activity 4.56566449113494 bayes_pls_golite062009
electron carrier activity 1.9747415675561 bayes_pls_golite062009
catalytic activity 0.672192331361968 bayes_pls_golite062009
oxidoreductase activity, acting on sulfur group of donors 0.429973830241021 bayes_pls_golite062009
protein binding 0.195947179962724 bayes_pls_golite062009
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle