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View Structure Prediction Details

Protein: thoc5-PA
Organism: Drosophila melanogaster
Length: 616 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for thoc5-PA.

Description E-value Query
Range
Subject
Range
gi|114685757 - gi|114685757|ref|XP_001135466.1| PREDICTED: THO complex 5 isoform 3 [Pan troglodytes]
493.0 [0..3] [605..32]

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Predicted Domain #1
Region A:
Residues: [1-338]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 METILNTQFD QLQKAIEGIK EAKSKGQSTD EARIATTLMF VALKHANREV KHKIKAGRDK  60
   61 LHLEKCKVDL SRLQLQNLLY EVSHLKKEIV RCQKFKSRDT SLELLSEAEY SSELPDMPND 120
  121 AEELSSHKQH LHRLDCELRL RKALDKQYSA LLSSKQELLQ DNLSHAQRYV SFAPALRTLQ 180
  181 SATKPLHDAL QLSLDVEWKL SAVVKYLPKP LYVLFIVLQS LQRVSEEQSF TAEVVGYESE 240
  241 AQMQELLKEK KCSTLNYRQT KKESGDREKI ADKNNLDDSL APHPLHICLT IGAAGSNQLV 300
  301 LQIRYFDFIK CATVWGQLNC SRNANGQGDT NFVHHLLR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 24.221849
Match: 1i84S
Description: Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [339-447]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HLYPNDLGNE LPIPGIQYEL RSSDLTAEEC VRYLKAKDYG KPFCWLQSMC SIATVNSSML  60
   61 YKHELNLNKN NKEIIDRIAR RLNSWQRLSQ QIRGLTFKDI DLYSLQENI

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [448-616]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YPAGLSCSLV QWTAITHEEL HSQISDALNS SSADKGITYN SYRAVIVRGS AKMECFIRIP  60
   61 SNYPLEMPLW ILNVHWNGCL TAQNNSAIKM MEFWTNSLQP KHLEPNDCIL YAQLFRTIYS 120
  121 FDIFLETEGS MQNTIEYNKE KPYISAFAKR SRSRPYKYIK KGSVYAFKQ

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.348 N/A N/A a.121.1 Tetracyclin repressor-like, C-terminal domain
View Download 0.248 N/A N/A a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.220 N/A N/A f.36.1 Neurotransmitter-gated ion-channel pransmembrane pore
View Download 0.212 N/A N/A a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.209 N/A N/A a.24.17 Group V grass pollen allergen


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle