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View Structure Prediction Details

Protein: Gmer-PA
Organism: Drosophila melanogaster
Length: 321 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Gmer-PA.

Description E-value Query
Range
Subject
Range
gi|56420684, gi|... - gi|56420684|ref|YP_148002.1| UDP-glucose 4-epimerase [Geobacillus kaustophilus HTA426], gi|56380526|...
315.0 [0..4] [320..2]

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Predicted Domain #1
Region A:
Residues: [1-321]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKKVLVTGGT GLVGKALEAV IKEQSPEDEQ WFFAGSKDAD LTNLAATQAL FAREKPTHVI  60
   61 HLAAMVGGLF HNMNNNLDFL RNNLLINDNV LQTAHEQGCV KVVSCLSTCI FPDKTSYPID 120
  121 ETMVHNGPPH PSNYGYSYAK RLIDVQNHAY HDKYGRVYTS VIPCNIFGPH DNYNPEVSHV 180
  181 IPGMIYRMHQ LVTEKTDVPE NDKVFTVFGS GMPLRQFVYS RDLAELMIWV LRNYESVEPI 240
  241 ILSADEVQEV TIFEVAQAVA KAFNFNGRLV CDTSKSDGQY KKTASNAKLR SFLPDYAFTD 300
  301 LETAINASVK WYIENYDQAR K

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 62.69897
Match: 1e6uA
Description: GDP-4-keto-6-deoxy-d-mannose epimerase/reductase (GDP-fucose synthetase)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
catalytic activity 1.79741889688267 bayes_pls_golite062009
oxidoreductase activity, acting on CH-OH group of donors 1.03956654822048 bayes_pls_golite062009
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 0.82673050487418 bayes_pls_golite062009
protein binding 0.381642189238843 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle