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View Structure Prediction Details

Protein: CG15227-PA
Organism: Drosophila melanogaster
Length: 291 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CG15227-PA.

Description E-value Query
Range
Subject
Range
CAH2_TRIHK - Carbonic anhydrase 2 OS=Tribolodon hakonensis GN=ca2 PE=2 SV=3
319.0 [0..47] [287..2]
gi|35505160, gi|... - gi|40363537|ref|NP_954685.1| carbonic anhydrase II [Danio rerio], gi|35505160|gb|AAH57412.1| Carboni...
317.0 [0..48] [288..3]
gi|22252956 - gi|22252956|gb|AAM94169.1| erythrocyte carbonic anhydrase [Lepisosteus osseus]
314.0 [0..47] [288..2]
gi|223999 - gi|223999|prf||1007140A anhydrase II,carbonic
314.0 [0..47] [288..1]
gi|13786892, gi|... - gi|13786892|pdb|1I9Q|A Chain A, Carbonic Anhydrase Ii (F131v) Complexed With 4- (Aminosulfonyl)-N-[(...
314.0 [0..47] [287..1]
gi|60831506 - gi|60831506|gb|AAX36973.1| carbonic anhydrase II [synthetic construct]
313.0 [0..47] [287..2]

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Predicted Domain #1
Region A:
Residues: [1-291]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIDLCWLKFI RAFGLVMQLA EESRFIMMLI SCTMAVAFIL NLYSGRTIFQ DVVNAVGNRR  60
   61 LEMKLAKQPS PITIPESNMI KRQLKMPLHW TYYEDLPMAT VLENNGNTVI MRIYTANNFM 120
  121 PQLSGAELLG RYQFVEAIFK WGSLKSEHSI GKHNFCLELQ ALHRCAQLNN NFEYLTLSYL 180
  181 FALSHVKNEH LKQVTDHLKW ISQPGSSIEL PPFHLESLLQ PFGSGYFSYE GTYDNGDVVL 240
  241 PTTWLINRKI SVVDSRQLSE FEALYGRNGN RNCKNGREKQ PLGNRNVYFN I

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 85.522879
Match: 1g3zA
Description: Carbonic anhydrase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
catalytic activity 0.442798720055561 bayes_pls_golite062009
lyase activity 0.0449485606126898 bayes_pls_golite062009
carbon-oxygen lyase activity 0.0281056088528198 bayes_pls_golite062009
hydro-lyase activity 0.0251875929678702 bayes_pls_golite062009
carbonate dehydratase activity 0.0175643366292402 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle