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View Structure Prediction Details

Protein: exu-PC, exu-PA, ...
Organism: Drosophila melanogaster
Length: 532 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for exu-PC, exu-PA, ....

Description E-value Query
Range
Subject
Range
gi|241021, gi|103245 - gi|241021|gb|AAB20673.1| exuperantia [Drosophila melanogaster], pir||S18643 maternal exuperantia pro...
671.0 [0..1] [532..1]

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Predicted Domain #1
Region A:
Residues: [1-233]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVADNIDAGV AIAVADQSSS PVGDKVELPA GNYILVGVDI DTTGRRLMDE IVQLAAYTPT  60
   61 DHFEQYIMPY MNLNPAARQR HQVRVISIGF YRMLKSMQTY KIIKSKSEIA ALKDFLNWLE 120
  121 QLKTKAGPSS DGIVLIYHEE RKFIPYMILE SLKKYGLLER FTASVKSFAN SINLAKASIG 180
  181 DANIKNYSLR KLSKILSTTK EEDAACSAST SGSGSGLGSG SSMVSDSVSI SPR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 36.69897
Match: 1j53A
Description: N-terminal exonuclease domain of the epsilon subunit of DNA polymerase III
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
hydrolase activity 1.44290958761413 bayes_pls_golite062009
nuclease activity 1.00688665458061 bayes_pls_golite062009
binding 0.715089866064182 bayes_pls_golite062009
hydrolase activity, acting on ester bonds 0.642554618883525 bayes_pls_golite062009
ribonuclease activity 0.479837770977411 bayes_pls_golite062009
RNA binding 0.217121396162622 bayes_pls_golite062009
3'-5' exonuclease activity 0.0891359324170981 bayes_pls_golite062009
protein binding 0.035326007863533 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [234-414]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DSTVTNGDDK QSSKNAVQGK RELFDGNASV RAKLAFDVAL QLSNSDGKPE PKSSEALENM  60
   61 FNAIRPFAKL VVSDVLELDI QIENLERQNS FRPVFLNYFK TTLYHRVRAV KFRIVLAENG 120
  121 FDLNTLSAIW AEKNIEGLDI ALQSIGRLKS KDKAELLELL DSYFDPKKTT VKPVVKGNSN 180
  181 N

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [415-532]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NNNYRRRNRR GGRQSVKDAR PSSSPSASTE FGAGGDKSRS VSSLPDSTTK TPSPNKPRMH  60
   61 RKRNSRQSLG ATPNGLKVAA EISSSGVSEL NNSAPPAVTI SPVVAQPSPT PVAITASN

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle