YRC Public Data Repository - Protein Structure Prediction

Protein:	MED8-PA
Organism:	Drosophila melanogaster
Length:	252 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MED8-PA.

Description	E-value	Query Range	Subject Range
gi\|17945348 - gi\|17945348\|gb\|AAL48730.1\| RE16440p [Drosophila melanogaster]	405.0	[0..1]	[252..1]
gi\|195154871, gi... - gi\|195154871\|ref\|XP_002018336.1\| GL16821 [Drosophila persimilis], gi\|194114132\|gb\|EDW36175.1\| GL1682... gi\|54636331, gi\|... - gi\|54636331\|gb\|EAL25734.1\| GA12583 [Drosophila pseudoobscura pseudoobscura], gi\|125809534\|ref\|XP_001... gi\|54636331\|gb\|E... - GA12583-PA [Drosophila pseudoobscura], GA12583 [Drosophila pseudoobscura pseudoobscura]	398.0	[0..1]	[252..1]
gi\|114555980 - gi\|114555980\|ref\|XP_001173530.1\| PREDICTED: mediator of RNA polymerase II transcription subunit MED8...	394.0	[0..1]	[252..1]
gi\|162859377, gi... - gi\|48762702\|ref\|NP_001001651.1\| mediator of RNA polymerase II transcription subunit MED8 isoform 3 [...	391.0	[0..1]	[252..1]
gi\|62649532, gi\|... - gi\|62649532\|ref\|XP_342895.2\| PREDICTED: similar to mediator of RNA polymerase II transcription subun...	390.0	[0..1]	[252..1]
MED8_MOUSE - Mediator of RNA polymerase II transcription subunit 8 OS=Mus musculus GN=Med8 PE=1 SV=1	385.0	[0..1]	[252..1]
gi\|194665848, gi... - gi\|76614400\|ref\|XP_872460.1\| PREDICTED: similar to Mediator of RNA polymerase II transcription subun...	383.0	[0..1]	[252..1]

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Predicted Domain #1

Region A:
Residues: [1-147]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQRDEKLFEL TLDTVLQRLN DLKLAVLSMI QKLELEYETI NWPTFLDNFA IISSHLTGLT  60
   61 KILAKEQCPP LRNRTVLPLL VSMDRDDTLI NITEGRVPVF SHDIVPDYLR TRPDPITEQK 120
  121 MLQNEQKAAN LTNDAAMKQV TQYNKVV

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [148-252]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SHVLDMVSKA REEWEIESSS RTGIQQTSSM ADTQLLVAAV GMGKGLKLTN YGPGPGMMVP  60
   61 PSIRAPSPMG GPAMSPGNVQ QQLGKAPSAV KTNIKSANQV HPFSR

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

		MCM Score	GO Score	GO Term	SCOP Match	SCOP Description
View	Download	0.457	N/A	N/A	d.58.3	Protease propeptides/inhibitors
View	Download	0.265	N/A	N/A	d.58.11	EF-G/eEF-2 domains III and V
View	Download	0.219	N/A	N/A	a.60.2	RuvA domain 2-like

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits