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View Structure Prediction Details

Protein: CG11055-PC, CG11...
Organism: Drosophila melanogaster
Length: 881 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CG11055-PC, CG11....

Description E-value Query
Range
Subject
Range
gi|194194308, gi... - gi|56201298|dbj|BAD72901.1| unnamed protein product [Drosophila simulans], gi|195585033|ref|XP_00208...
704.0 [0..1] [868..1]

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Predicted Domain #1
Region A:
Residues: [1-243]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIDAASAERA SPQFIALFND NLKLGHEDDG PQAVNGKDTH QHVPADLEAT YGTLYAACQD  60
   61 HAAFFARDHT EFGQRLHAAH IAWQDFIVLA NRLVQQIDAF AHEYDFDEQT PGNGYRSFIY 120
  121 VTNACIAHGI SICQQLTATR STIFFRKKFY MKEVEACSQL LSSLCTCLQY LLILRQWSAS 180
  181 TGDLFACGNH TAEQLFELGD TINQYCFYGR CLGFQYGDSI RGVLRFLGIS MASYSESYYS 240
  241 QEG

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [244-325]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DGPIVKTTRS LWTSGKYLMN PELRARRIVN ISQNAKIDFC KSFWFLAESE MMHKLPSIVG  60
   61 SSIKVNRLIE LPAEPLKLPR RK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [326-618]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NFKASDNLSS DVNQNQGDGD FVEIPVPTAH LGPGLPVSVR LLSARRRSGM LGEGRYRGWH  60
   61 KPIPPSPSIL FHCHGGGFVA QSSKSHELYL RDWAVALDCP ILSVDYSLAP EAPFPRALQE 120
  121 VYYAYCWLLN NTELLGTTAE RVVCAGDSAG ANLSIGVALK CIEQGVRVPD GLFLAYCPTL 180
  181 VSFVPSPARL LCLMDPLLPF GFMMRCLRAY AAPAQETLQQ NAKQVEDAAQ IRNVPKSNVG 240
  241 SLNSSRRTSM ARSPLSPLEA SMNPDDESSD TFASASASYH SQTVERTDLP HTE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 56.522879
Match: 2c7bA
Description: The Crystal Structure of EstE1, a New Thermophilic and Thermostable Carboxylesterase Cloned from a Metagenomic Library
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [619-881]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GDNSSCVSFE DDSQPIVHYP IEISADPPKD TASAAYIDNF LDKYLIDTAT MEVTEETAPE  60
   61 AVQAQANGHA KISSDDDILV ETGRDLVAID TLQGRLQEAV NNITNTLTRC TQSYEIHGSN 120
  121 VMAQQDVRNM DALIARSPSE EFAFDVPKDP FLSPYWASDE WLSQLPETKI LTLNMDPCLD 180
  181 DCVMFAKKLK RLGRQVDLEI LEGLPHGFLN FTMLSNEAME GSKKCIKSLQ TLLQTDSKTK 240
  241 NIDKANSMDE EESSSPSASL AAS

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 5.7
Match: 1jjiA
Description: Carboxylesterase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
hydrolase activity 0.415836030391699 bayes_pls_golite062009
catalytic activity 0.397872257482442 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle