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View Structure Prediction Details

Protein: par-1-PF
Organism: Drosophila melanogaster
Length: 1098 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for par-1-PF.

Description E-value Query
Range
Subject
Range
par-1-PC, par-1-... - The gene par-1 is referred to in FlyBase by the symbol Dmel\par-1 (CG8201, FBgn0260934). It is a pro...
660.0 [0..1] [1098..1]

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Predicted Domain #1
Region A:
Residues: [1-124]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEATTTTTPD LNRGDATRKS VRLYAARKGA APAPPKLSVA PSSNQNSNHS SNNNNSSSNL  60
   61 PETEKEMELR QTHLANKDLD GATEDDSIVE LRRRDAQATP LPRIAVSALP TLQPHPTPKE 120
  121 RQKP

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [125-208]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PMPRLLSTED DAGVSFALGS IEKHIHNVEE SFKQQQQNQQ SQSSMDVMKL EIKRKQSKRY  60
   61 GETENLLRPG ISDMSSENDF QYLG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 12.30103
Match: 1f3mA
Description: pak1 autoregulatory domain
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [209-395]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GRRAGELDDS NELMLSEFQR GSDGRNSIGA YSKNSAAAAN GANAVKAKLA RTASDTKNND  60
   61 TVLAMRATFK QKQHLQDEKQ PAVWRPAGTG PTPAARSSSS TTSTSGSASR GGSSSSVVDG 120
  121 VAPSKLTATT ISASKRREEN LRQFEALLAQ KSSHRHGASG ASGTGSNAAS SKRRSDRPIV 180
  181 APIPPYN

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [396-740]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SSRAEHVTSS TRHSVDPRSH SGHESRSGTA STHPPVGHHP TSRVPSVVAN RSNVYSNNAA  60
   61 QGSPNMQMRS SAPMRWRATE EHIGKYKLIK TIGKGNFAKV KLAKHLPTGK EVAIKIIDKT 120
  121 QLNPGSLQKL FREVRIMKML DHPNIVKLFQ VIETEKTLYL IMEYASGGEV FDYLVLHGRM 180
  181 KEKEARVKFR QIVSAVQYCH QKRIIHRDLK AENLLLDSEL NIKIADFGFS NEFTPGSKLD 240
  241 TFCGSPPYAA PELFQGKKYD GPEVDVWSLG VILYTLVSGS LPFDGSTLRE LRERVLRGKY 300
  301 RIPFYMSTDC ENLLRKFLVL NPAKRASLET IMGDKWMNMG FEEDE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 52.09691
Match: 1qcfA
Description: Hemapoetic cell kinase Hck; Hemopoetic cell kinase Hck; Haemopoetic cell kinase Hck
Matching Structure (courtesy of the PDB):

Predicted Domain #5
Region A:
Residues: [741-804]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LKPYIEPKAD LADPKRIEAL VAMGYNRSEI EASLSQVRYD DVFATYLLLG RKSTDPESDG  60
   61 SRSG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 98.0
Match: 2qnjA
Description: No description for 2qnjA was found.

Predicted Domain #6
Region A:
Residues: [805-1005]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SSLSLRNISG NDAGANAGSA SVQSPTHRGV HRSISASSTK PSRRASSGAE TLRVGPTNAA  60
   61 ATVAAATGAV GAVNPSNNYN AAGSAADRAS VGSNFKRQNT IDSATIKENT ARLAAQNQRP 120
  121 ASATQKMLTT ADTTLNSPAK PRTATKYDPT NGNRTVSGTS GIIPRRSTTL YEKTSSTEKT 180
  181 NVIPAETNSG SAAPAGKGHT K

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #7
Region A:
Residues: [1006-1098]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SASVSSPRPS TDGCVSVSND PLGTRMASAV KSSRHFPRNV PSRSTFHSGQ TRARNNTALE  60
   61 YSGTSGASGD SSHPGRMSFF SKLSSRFSKR PNQ

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


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