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View Structure Prediction Details

Protein: Hsf-PA
Organism: Drosophila melanogaster
Length: 691 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Hsf-PA.

Description E-value Query
Range
Subject
Range
Hsf-PC - The gene Heat shock factor is referred to in FlyBase by the symbol Dmel\Hsf (CG5748, FBgn0001222). I...
564.0 [0..1] [691..1]

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Predicted Domain #1
Region A:
Residues: [1-148]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSRSRSSAKA VQFKHESEEE EEDEEEQLPS RRMHSYGDAA AIGSGVPAFL AKLWRLVDDA  60
   61 DTNRLICWTK DGQSFVIQNQ AQFAKELLPL NYKHNNMASF IRQLNMYGFH KITSIDNGGL 120
  121 RFDRDEIEFS HPFFKRNSPF LLDQIKRK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 39.69897
Match: 1hksA
Description: SOLUTION STRUCTURE OF THE DNA-BINDING DOMAIN OF DROSOPHILA HEAT SHOCK TRANSCRIPTION FACTOR
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [149-249]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ISNNKNGDDK GVLKPEAMSK ILTDVKVMRG RQDNLDSRFS AMKQENEVLW REIASLRQKH  60
   61 AKQQQIVNKL IQFLITIVQP SRNMSGVKRH VQLMINNTPE I

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 10.102373
Match: PF00447.8
Description: No description for PF00447.8 was found.

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [250-355]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DRARTTSETE SESGGGPVIH ELREELLDEV MNPSPAGYTA ASHYDQESVS PPAVERPRSN  60
   61 MSISSHNVDY SNQSVEDLLL QGNGTAGGNI LVGGAASPMA QSVSQS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [356-526]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PAQHDVYTVT EAPDSHVQEV PNSPPYYEEQ NVLTTPMVRE QEQQKRQQLK ENNKLRRQAG  60
   61 DVILDAGDIL VDSSSPKAQR TSIQHSTQPD VMVQPMIIKS EPENSSGLMD LMTPANDLYS 120
  121 VNFISEDMPT DIFEDALLPD GVEEAAKLDQ QQKFGQSTVS SGKFASNFDV P

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [527-691]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TNSTLLDANQ ASTSKAAAKA QASEEEGMAV AKYSGAENGN NRDTNNSQLL RMASVDELHG  60
   61 HLESMQDELE TLKDLLRGDG VAIDQNMLMG LFNDSDLMDN YGLSFPNDSI SSEKKAPSGS 120
  121 ELISYQPMYD LSDILDTDDG NNDQEASRRQ MQTQSSVLNT PRHEL

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


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