YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: Khc-PA
Organism: Drosophila melanogaster
Length: 975 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Khc-PA.

Description E-value Query
Range
Subject
Range
gi|27882435 - gi|27882435|gb|AAH44720.1| Kif3a protein [Mus musculus]
364.0 [0..3] [364..5]

Back

Predicted Domain #1
Region A:
Residues: [1-297]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSAEREIPAE DSIKVVCRFR PLNDSEEKAG SKFVVKFPNN VEENCISIAG KVYLFDKVFK  60
   61 PNASQEKVYN EAAKSIVTDV LAGYNGTIFA YGQTSSGKTH TMEGVIGDSV KQGIIPRIVN 120
  121 DIFNHIYAME VNLEFHIKVS YYEIYMDKIR DLLDVSKVNL SVHEDKNRVP YVKGATERFV 180
  181 SSPEDVFEVI EEGKSNRHIA VTNMNEHSSR SHSVFLINVK QENLENQKKL SGKLYLVDLA 240
  241 GSEKVSKTGA EGTVLDEAKN INKSLSALGN VISALADGNK THIPYRDSKL TRILQES

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 87.522879
Match: 1mkjA
Description: Kinesin
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
microtubule motor activity 7.68336791348661 bayes_pls_golite062009
plus-end-directed microtubule motor activity 4.97507344344589 bayes_pls_golite062009
microfilament motor activity 4.176620576177 bayes_pls_golite062009
motor activity 4.04927796049806 bayes_pls_golite062009
nucleoside-triphosphatase activity 2.95079405147356 bayes_pls_golite062009
pyrophosphatase activity 2.87427509025394 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides 2.85499564954033 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 2.85178667290149 bayes_pls_golite062009
actin-dependent ATPase activity 2.77140616759165 bayes_pls_golite062009
microtubule plus-end binding 2.71138928021716 bayes_pls_golite062009
tubulin binding 2.67743463093593 bayes_pls_golite062009
binding 2.64537357529343 bayes_pls_golite062009
microtubule binding 2.59155206524122 bayes_pls_golite062009
transporter activity 2.58140740499725 bayes_pls_golite062009
cytoskeletal protein binding 2.4101693596493 bayes_pls_golite062009
transmembrane transporter activity 2.39695871109024 bayes_pls_golite062009
ATPase activity 2.39535714892224 bayes_pls_golite062009
ATPase activity, coupled 2.18396165590908 bayes_pls_golite062009
ATP-dependent DNA helicase activity 2.07967285635739 bayes_pls_golite062009
actin binding 1.75397031486306 bayes_pls_golite062009
hydrolase activity 1.57549510726226 bayes_pls_golite062009
general RNA polymerase II transcription factor activity 1.40384549325664 bayes_pls_golite062009
helicase activity 1.33212695797068 bayes_pls_golite062009
substrate-specific transporter activity 1.29730375126024 bayes_pls_golite062009
protein binding 1.22129154759482 bayes_pls_golite062009
DNA-dependent ATPase activity 1.07479235523606 bayes_pls_golite062009
purine nucleotide binding 0.929901285538132 bayes_pls_golite062009
nucleotide binding 0.922442819194247 bayes_pls_golite062009
purine ribonucleotide binding 0.920987930180051 bayes_pls_golite062009
ribonucleotide binding 0.920926158369519 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 0.906554174337376 bayes_pls_golite062009
nucleic acid binding 0.777787753097919 bayes_pls_golite062009
actin filament binding 0.728264616959762 bayes_pls_golite062009
structure-specific DNA binding 0.579644950922817 bayes_pls_golite062009
kinetochore binding 0.505370954958131 bayes_pls_golite062009
DNA binding 0.479412476059825 bayes_pls_golite062009
GTPase activity 0.437665353870877 bayes_pls_golite062009
active transmembrane transporter activity 0.434775387083003 bayes_pls_golite062009
ATP binding 0.41092997612902 bayes_pls_golite062009
adenyl ribonucleotide binding 0.385813421701492 bayes_pls_golite062009
adenyl nucleotide binding 0.377870145186619 bayes_pls_golite062009
ion transmembrane transporter activity 0.355466224802969 bayes_pls_golite062009
RNA helicase activity 0.34746349346164 bayes_pls_golite062009
histone acetyltransferase activity 0.328186246219424 bayes_pls_golite062009
lysine N-acetyltransferase activity 0.328186246219424 bayes_pls_golite062009
transcription regulator activity 0.312171320541728 bayes_pls_golite062009
ATP-dependent RNA helicase activity 0.30832907234141 bayes_pls_golite062009
RNA-dependent ATPase activity 0.29532978396745 bayes_pls_golite062009
primary active transmembrane transporter activity 0.294474570607914 bayes_pls_golite062009
P-P-bond-hydrolysis-driven transmembrane transporter activity 0.282352478532746 bayes_pls_golite062009
ATP-dependent helicase activity 0.25143870859482 bayes_pls_golite062009
purine NTP-dependent helicase activity 0.25143870859482 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances 0.220608508617331 bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of substances 0.219533217661421 bayes_pls_golite062009
ATPase activity, coupled to movement of substances 0.219157471322311 bayes_pls_golite062009
protein transporter activity 0.178442534411253 bayes_pls_golite062009
DNA helicase activity 0.17029946873911 bayes_pls_golite062009
mismatched DNA binding 0.13866566261611 bayes_pls_golite062009
minus-end-directed microtubule motor activity 0.068779631341469 bayes_pls_golite062009
cation transmembrane transporter activity 0.0254369227200564 bayes_pls_golite062009
structural constituent of cytoskeleton 0.0111338193708552 bayes_pls_golite062009
RNA binding 0.00414926067713517 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [298-382]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LGGNARTTIV ICCSPASFNE SETKSTLDFG RRAKTVKNVV CVNEELTAEE WKRRYEKEKE  60
   61 KNARLKGKVE KLEIELARWR AGETV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 10.0
Match: 3kinB
Description: KINESIN (DIMERIC) FROM RATTUS NORVEGICUS
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [383-665]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KAEEQINMED LMEASTPNLE VEAAQTAAAE AALAAQRTAL ANMSASVAVN EQARLATECE  60
   61 RLYQQLDDKD EEINQQSQYA EQLKEQVMEQ EELIANARRE YETLQSEMAR IQQENESAKE 120
  121 EVKEVLQALE ELAVNYDQKS QEIDNKNKDI DALNEELQQK QSVFNAASTE LQQLKDMSSH 180
  181 QKKRITEMLT NLLRDLGEVG QAIAPGESSI DLKMSALAGT DASKVEEDFT MARLFISKMK 240
  241 TEAKNIAQRC SNMETQQADS NKKISEYEKD LGEYRLLISQ HEA

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 2.84
Match: 1c1gA
Description: Tropomyosin
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [666-975]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RMKSLQESMR EAENKKRTLE EQIDSLREEC AKLKAAEHVS AVNAEEKQRA EELRSMFDSQ  60
   61 MDELREAHTR QVSELRDEIA AKQHEMDEMK DVHQKLLLAH QQMTADYEKV RQEDAEKSSE 120
  121 LQNIILTNER REQARKDLKG LEDTVAKELQ TLHNLRKLFV QDLQQRIRKN VVNEESEEDG 180
  181 GSLAQKQKIS FLENNLDQLT KVHKQLVRDN ADLRCELPKL EKRLRCTMER VKALETALKE 240
  241 AKEGAMRDRK RYQYEVDRIK EAVRQKHLGR RGPQAQIAKP IRSGQGAIAI RGGGAVGGPS 300
  301 PLAQVNPVNS 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 5.30103
Match: 2i1jA
Description: No description for 2i1jA was found.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle