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View Structure Prediction Details

Protein: FBpp0292771, Lap1-PA
Organism: Drosophila melanogaster
Length: 849 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FBpp0292771, Lap1-PA.

Description E-value Query
Range
Subject
Range
SCRIB_DANRE - Protein scribble homolog OS=Danio rerio GN=scrib PE=1 SV=1
432.0 [0..4] [849..1]

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Predicted Domain #1
Region A:
Residues: [1-393]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPLLSKCFPC FKFKREEVID KLDYSNTPLT DFPEVWQHER TLEELYLSTT RLQALPPQLF  60
   61 YCQGLRVLHV NSNNLESIPQ AIGSLRQLQH LDLNRNLIVN VPEEIKSCKH LTHLDLSCNS 120
  121 LQRLPDAITS LISLQELLLN ETYLEFLPAN FGRLVNLRIL ELRLNNLMTL PKSMVRLINL 180
  181 QRLDIGGNEF TELPEVVGEL KSLRELWIDF NQIRRVSANI GKLRDLQHFE ANGNLLDTLP 240
  241 SELSNWRNVE VLSICSNSLE AFPFSVGMLK SLVTFKCESN GLTELPDSIS YLEQLEELVL 300
  301 SHNKLIRLPS TIGMLRSLRF LFADDNQLRQ LPDELCSCQQ LSVLSVANNQ LSALPQNIGN 360
  361 LSKMKVLNVV NNYINALPVS MLNLVNLTSM WLS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 43.522879
Match: 2omuA
Description: No description for 2omuA was found.

Predicted Domain #2
Region A:
Residues: [394-491]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DNQSQPLVPL QYLDASTKTQ LTCFMLPQVT FKMNSIQAQQ QAQEQYEFVY ANQQQPHASP  60
   61 SRRICFAEEA TILSNAKAQP APNYPSFVAA PPTPTPDQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 35.69897
Match: 2id5A
Description: No description for 2id5A was found.

Predicted Domain #3
Region A:
Residues: [492-632]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAGSVRLMRS PTPYPKELRQ MSKYVRQAQA ATSSANASEV REARVVTNGQ IHCDSNNANQ  60
   61 DVVDQATTSA IYGIAPETTH IYGVYQQPQQ MAHPVPTQEY YGLPLVNYEA HYQQLYVEAN 120
  121 TPLPTTHLNG DQDYELQPLQ Q

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [633-699]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QPMQQQALPT PRLEPPPYHI ARVYTKKTPE DLNLYESMRQ RKQQQQLQEQ TIYQDALNSN  60
   61 SNFKTTA

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [700-849]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IGAQDVEESV DQLDYQNNIS NNLEPNPEEE DQELDDTMSQ HSLNSTATNN TSKASHKKST  60
   61 WIFGVHKNPT VKQVTLKWEN SIGFDIAELL NQVGIFVSSI TPNTNAARLL NLNDKLLEID 120
  121 GYDLTNANLS DAKRVLLNCG TVMNIMLSRK 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 26.0
Match: 1tp3A
Description: PDZ3 domain of PSD-95 protein complexed with KKETPV peptide ligand
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle