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View Structure Prediction Details

Protein: Spred-PA
Organism: Drosophila melanogaster
Length: 426 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Spred-PA.

Description E-value Query
Range
Subject
Range
gi|76629737 - gi|76629737|ref|XP_597289.2| PREDICTED: similar to sprouty-related protein with EVH-1 domain 2 isofo...
443.0 [0..1] [426..1]

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Predicted Domain #1
Region A:
Residues: [1-123]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTEGHESDFL VTVRAQVMTR DESTEGWLPL AGGGLANVSI RKRARLSPLA SGHDYIIYGQ  60
   61 RISDQSVILS CVINRDLKYY KVMPTFHHWR AGKQRNGLTF QTAADARAFD KGVLRAYNEL 120
  121 IDG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 44.39794
Match: 2jp2A
Description: No description for 2jp2A was found.

Predicted Domain #2
Region A:
Residues: [124-294]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LAKSNPTIIC PPLTKYDSVG EDDVFMTLDL PVESESLQKI HSSPEGSEKS HKSVSNNSDS  60
   61 EKLPPPPIHY ISTDKTSATT SPPDAPPASA APSPATAGQI AASENYSYVT LTAVHHDYNY 120
  121 PVVDQPVGAQ VLNARRESIS ALKKRNALEA AQAMAAAQTA AGGGLACRDG G

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [295-426]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SGKPLHKPNV SDILKKETRL RCRYCHELYS EDFNRRGACE YAPDAFRSGY ECISGMGCAR  60
   61 CMIYHCMSDA EGETAQHPCD CSASEAGCSK RWLGLAILSL FVPCLWCYPP LRACHLAGIH 120
  121 CGLCGGQHKP HV

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 0.971
Match: 1kx4I
Description: X-Ray Structure of the Nucleosome Core Particle, NCP146b, at 2.6 A Resolution
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle